Results 91 to 100 of about 5,024 (202)

СИНТЕЗ 4-ДИФТОРОМЕТИЛ-1Н-ПІРАЗОЛ-3-КАРБОНОВИХ КИСЛОТ [PDF]

, 2014
Розроблено ефективний синтетичний підхід до 4-дифторометил-1Н-піразол-3-карбонових кислот, який базується на дифторометилюванні етил 4-форміл-1Н-піразол-3-карбоксилатів діетиламіносульфуртрифторидом і наступному гідролізі утворених етил 4-дифторометил ...
Барус, М.М., Бездудний, А.В., Братенко, М.К., Вовк, М.В.   +3 more
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Strategies to inhibit tumour associated integrin receptors: rationale for dual and multi-antagonists [PDF]

, 2014
YesThe integrins are a family of 24 heterodimeric transmembrane cell surface receptors. Involvement in cell attachment to the extracellular matrix, motility, and proliferation identifies integrins as therapeutic targets in cancer and associated ...
Albelda S. M., Amirkhosravi A., Aumailley M., Bandyopadhyay A., Barker P. L., Batt D. G., Bello L., Benfatti F., Bennett J. S., Bianchi-Smiraglia A., Bisanz K., Bochen A., Boys M. L., Bretschi M., Bretschi M., Brooks P. C., Buergy D., Burbridge M. F., Böger C., Calderwood D. A., Calvete J. J., Calvete J. J., Carey C. M., Chen Q., Chico T. J. A., Christoforides C., Chu F. M., Chung K.-H., Cohen S. A., Cox D., Dardik R., Davenport R. J., Davis F. B., De Corte B. L., De S., Dechantsreiter M. A., Dome B., Duan X. P., Engebraaten O., Engleman V. W., Erdreich-Epstein A., Friedlander M., Gasparini G., Gentilucci L., Gomes N., Goodman S. L., Goodman S. L., Goodman S. L., Hailey S., Harms J. F., Heidenreich A., Helen M. Sheldrake, Henderson N. C., Humphries J. D., Ishikawa M., Ishikawa M., Kang I.-C., Kerr J. S., Kim S., Knowles L. M., Kubota D., Kubota D., Kumar C. C., Laurence H. Patterson, Laurens N., Letourneau J. J., Lin E., Liu Y., Lonsdorf A. S., Lucena S. E., Malik G., Marelli U. K., Marinelli L., Marinelli L., Marinelli L., Martin P. L., Martin S., Mas-Moruno C., Mas-Moruno C., Matsuno H., Maubant S., Max R., McCabe N. P., Meerovitch K., Menendez J. A., Minea R., Minea R. O., Mitjans F., Morjen M., Mullamitha S. A., Naber H. P., Nabors L. B., Nadrah K., Nagae M., Oleksowicz L., Osterkamp F., O’Day S., O’Day S. J., Palumbo J. S., Parvani J. G., Pecheur I., Peishoff C. E., Perron-Sierra F., Pfaff M., Pontes-Júnior J., Reinmuth N., Reynolds A. R., Romanov V. I., Ross F. P., Scarborough R. M., Scarborough R. M., Scaringi C., Schaffner F., Schittenhelm J., Schittenhelm J., Schmieder A. H., Schneider J. G., Shannon K. E., Sheldrake H. M., Shih C.-H., Simon K. O., Sloan E. K., Smallheer J. M., Sowmya G., Stachurska A., Steri V., Stragies R., Sung V., Swenson S., Sánchez E. E., The IMPACT-II Investigators., Timar J., Tolomelli A., Topol E. J., Trabocchi A., Trikha M., Trikha M., Trikha M., Trikha M., van den Hoogen C., van der Flier A., van der Horst G., van der Horst G., Vermorken J. B., Vogetseder A., Wan A. M., Wu Y. J., Xiao T., Zhang W., Zhao F., Zhao Y.   +150 more
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Metal‐Organic Framework/Organocatalyst Combinations as Powerful Multicatalytic Systems for Aerobic Oxidations

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
A multicatalytic strategy based on the simple combination of metal‐organic frameworks (MOFs) and organocatalysts is able to mediate challenging aerobic oxidation reactions. The use of earth‐abundant MOFs and commercially available (hydro)quinone co‐catalysts greatly simplify the generation of powerful multicatalytic systems, opening the door for the ...
Juan Camilo Arango‐Daza, Mathieu Onillon, Leonie Nork, Kunpot Mopoung, Yuttapoom Puttisong, Miguel A. Rivero‐Crespo   +5 more
wiley   +1 more source

Flash Pyrolysis – Synthetic and Mechanistic Aspects

CHIMIA, 1977
Some examples of synthetically useful flash pyrolysis reactions are presented, and the reaction mechanisms are discussed. Cyanocyclopentadienes, -indenes, and -pyrroles are produced by pyrolysis of the appropriate triazoloarenes or isatins, or as the ...
Curt Wentrup
doaj   +1 more source

Dimerisation, rhodium complex formation and rearrangements of N-heterocyclic carbenes of indazoles

Beilstein Journal of Organic Chemistry, 2014
Deprotonation of indazolium salts at low temperatures gives N-heterocyclic carbenes of indazoles (indazol-3-ylidenes) which can be trapped as rhodium complexes (X-ray analysis).
Zong Guan, Jan C. Namyslo, Martin H. H. Drafz, Martin Nieger, Andreas Schmidt   +4 more
doaj   +1 more source

Discovery of Novel N-Substituted Prolinamido Indazoles as Potent Rho Kinase Inhibitors and Vasorelaxation Agents

Molecules, 2017
Inhibitors of Rho kinase (ROCK) have potential therapeutic applicability in a wide range of diseases, such as hypertension, stroke, asthma and glaucoma.
Yangyang Yao, Renze Li, Xiaoyu Liu, Feilong Yang, Ying Yang, Xiaoyu Li, Xiang Shi, Tianyi Yuan, Lianhua Fang, Guanhua Du, Xiaozhen Jiao, Ping Xie   +11 more
doaj   +1 more source

Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C-H functionalisation [PDF]

, 2017
Expansion of the synthetic chemists' toolbox is currently a topic of great interest, with successes providing access to novel compounds and more efficient routes towards new and known pharmaceuticals and agrochemicals.
Chirila, Paula G, Whiteoak, Christopher
core   +1 more source

One-pot access to indazole fused-phenanthridinones via Rh(III)-catalyzed [4+2] annulation

Green Synthesis and Catalysis
An efficient synthesis of indazole fused phenanthridinones via Rh(III)-catalyzed inert C(sp2)-H activation/[4 ​+ ​2] annulation of 3-aryl-1H-indazoles with iodonium ylides has been developed, providing a strategy to access multi-conjugated π-system ...
Shumin Li, Jinke Chang, Jian Shen, Xiuling Cui   +3 more
doaj   +1 more source

A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors [PDF]

, 2018
Crystallography has guided the hybridization of two series of Trypanosoma brucei N-myristoyltransferase (NMT) inhibitors, leading to a novel highly selective series.
Brand, Stephen, Brenk, Ruth, Collie, Iain, Davies, Kenneth, Frearson, Julie A., Gilbert, Ian H., Hallyburton, Irene, Harrison, Justin R., Mok, Ngai, Norval, Suzanne, Read, Kevin D., Robinson, David A., Simeons, Frederick R. C., Smith, Alasdair, Smith, Victoria, Stojanovski, Laste, Thompson, Stephen, Torrie, Leah S., Wyatt, Paul G.   +18 more
core   +3 more sources

Circadian Variation of Locomotor Ability Mediated by Nitric Oxide in the Cerebellum [PDF]

, 2012
Honors Arts & Sciences Undergraduate Research Scholarship: $5000Previous research has revealed circadian differences in locomotor ability corresponding to improved performance during active period.
Spieldenner, James M.
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