Results 111 to 120 of about 9,407,399 (300)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
On the independence number of graph powers
Computational and Applied MathematicsAbstract Let G be a simple connected graph, and k be a positive integer. The k th graph power $$G^k$$
Rosário Fernandes, Rúben Palma
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
On the Number of Successes in Independent Trials
The Annals of Mathematical Statistics, 1965 The distribution of the number of successes in independent trials is shown to be bell-shaped of every order. The most likely number of successes is "almost uniquely" determined from the mean number and from the mean plus the largest and smallest probability of success on any trial.
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
On the Independence Number of Edge Chromatic Critical Graphs
Discussiones Mathematicae Graph Theory, 2014 In 1968, Vizing conjectured that for any edge chromatic critical graph G = (V,E) with maximum degree △ and independence number α (G), α (G) ≤. It is known that α (G) < |V |. In this paper we improve this bound when △≥ 4.
Pang Shiyou +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
New Formulae for the Decycling Number of Graphs
Discussiones Mathematicae Graph Theory, 2019 A set S of vertices of a graph G is called a decycling set if G−S is acyclic. The minimum order of a decycling set is called the decycling number of G, and denoted by ∇(G). Our results include: (a) For any graph G,, where T is taken over all the spanning
Yang Chao, Ren Han
doaj +1 more source