Results 101 to 110 of about 8,254,154 (302)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
АКТИВІЗАЦІЯ САМОСТІЙНОЇ НАВЧАЛЬНОЇ ДІЯЛЬНОСТІ СТУДЕНТІВ ЯК ПСИХОЛОГО-ПЕДАГОГІЧНА ПРОБЛЕМА
У статті висвітлюються основні аспекти сучасного психолого-педагогічного розуміння активізації самостійної навчальної діяльності студентів. На теоретичному рівні визначено вимоги, за дотримання яких активізація самостійної навчальної діяльності ...
І. В. Удод
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
This article presents a series of theoretical and practical aspects regarding the taxation of income from independent activities carried out under sports activity contracts.
Lucian CERNUȘCA
core +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Relationship between Children's Independent Activities and the Built Environment of Outdoor Activity Space in Residential Neighborhoods: A Case Study of Nanjing. [PDF]
Zhou Y, Wang M, Lin S, Qian C.
europepmc +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
ISPC Commentary on the Proposal for CRP3.3 - July 2010
Initial comments from the interim Independent Science and Partnership Council on the proposal for CRP 3.3: GRiSP, Global Rice Science Partnership - the first fast tracked CGIAR Mega Program ...
CGIAR Independent Science and Partnership Council
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The role of communication for EU independent fiscal institutions in times of escape clauses [PDF]
In recent years, communication has emerged as one of the defining characteristics of Independent Fiscal Institutions (IFIs), playing an increasingly important role in their activities. This study analyses the communication of 28 IFIs from 26 EU countries
Brinkman, Ebrien +8 more
core

