Results 131 to 140 of about 6,851,843 (255)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Employee or independent contractor?. Spanish
Title from PDF caption (viewed on December 7, 2021).Covers OCLC #1287891539, OCLC #707091328, and OCLC #461109352.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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The article deals with the problem concerning self-directed independent activities at a teacher training higher educational establishment on the basis of a task approach as the means of improvement student s knowledge quality.
M.A. Slyusarenko
doaj
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Employee or independent contractor?. Russian
Title from PDF caption (viewed on December 7, 2021).Covers OCLC #1287891563, OCLC #461112399, and OCLC #707093305.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
core
An analysis of accident trends and modeling of safety indices in an Indian construction organization [PDF]
Construction industry has been recognized as a hazardous industry in many countries due to distinct nature of execution of works.The accident rate in construction sector is high all over the world due to dynamic nature of work activities.
Rajaprasad, Sunku Venkata Siva +1 more
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Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

