Results 131 to 140 of about 6,851,843 (255)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Employee or independent contractor?. Spanish

open access: yes, 2007
Title from PDF caption (viewed on December 7, 2021).Covers OCLC #1287891539, OCLC #707091328, and OCLC #461109352.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

A PROBLEMATIC APPROACH TO THE ORGANIZATION OF INDEPENDENT WORK AS A MEANS OF IMPROVING THE QUALITY OF KNOWLEDGE OF STUDENTS OF THE PEDAGOGICAL UNIVERSITY

open access: yesОсвітній вимір, 2010
The article deals with the problem concerning self-directed independent activities at a teacher training higher educational establishment on the basis of a task approach as the means of improvement student s knowledge quality.
M.A. Slyusarenko
doaj  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Employee or independent contractor?. Russian

open access: yes, 2007
Title from PDF caption (viewed on December 7, 2021).Covers OCLC #1287891563, OCLC #461112399, and OCLC #707093305.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

An analysis of accident trends and modeling of safety indices in an Indian construction organization [PDF]

open access: yes, 2016
Construction industry has been recognized as a hazardous industry in many countries due to distinct nature of execution of works.The accident rate in construction sector is high all over the world due to dynamic nature of work activities.
Rajaprasad, Sunku Venkata Siva   +1 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

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