Results 101 to 110 of about 6,851,843 (255)

Project Activities as a Way of Developing Creative Independent Work of Foreign Students-Nonphylologies

Известия Южного федерального университета: Филологические науки, 2019
The aim of this article is to consider some problems of the use of method of projects in the process of learning Russian as a foreign language at preUniversity stage of education. Methodical organization of project activities of international learners in
Irina M. Yaroslavskaya
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Scientific Review in Oregon: A summary of the Independent Multidisciplinary Science Team's Technical Workshop [PDF]

This report synthesizes the findings of a workshop, held by Oregon’s Independent Multidisciplinary Science Team (IMST) in January, 2015, to discuss state-level science review and how to best formulate a panel to conduct scientific review of a broad suite
Independent Multidisciplinary Science Team
core   +4 more sources

Strategies for Activating Independent Learning Activities of Students in Biology Classes

Journal of Vasyl Stefanyk Precarpathian National University
The article is dedicated to methods of activating students' independent learning activities during biology classes. It is proved that independent work in education holds significant importance for both the learning process and students of general ...
Tetiana Mykytyn, Nataliia Dmytrus, Nadiia Kapets, Victoria Gniezdilova   +3 more
doaj   +1 more source

Suitable activities for independent learning

, 2020
Working independently helps students develop a series of skills and strategies that will continue to be useful in their future professional careers. Teachers in Higher Education (HE) have a role in facilitating Independent Learning (IL) for their students.
Carmen Martín de León, Cristina García Hermoso   +1 more
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Final Project Evaluation: Closing the Gap in NSW Independent Schools

, 2013
The Closing the Gap in NSW Independent Schools Project (2011-2012) was conceptualised and conducted by the NSW Association of Independent Schools (NSWAIS).
Graham, Lorraine, Berman, Jeanette
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source