Results 211 to 220 of about 16,633,437 (341)

RELATIONSHIP OF AN INDEPENDENT ACTIVITIES QUESTIONNAIRE TO PERFORMANCE DURING HIGH SCHOOL

, 1963
C. Schultz, R. Skager
semanticscholar   +1 more source

Mutations in the Caenorhabditis elegans Serotonin Reuptake Transporter MOD-5 Reveal Serotonin-Dependent and -Independent Activities of Fluoxetine

Journal of Neuroscience, 2001
R. Ranganathan, Elizabeth R Sawin, C. Trent, H. Robert Horvitz, Brendan D. Galvin, Brad Hersh, E. Miska, Ignacio Perez De La Cruz, Peter W. Reddien, H. Schwartz, R. Horvitz, H. Hughes   +11 more
semanticscholar   +1 more source

Association between the different basic activities of daily living on the Barthel index and community living, use of mobility aids, and the survival at 5 years. [PDF]

Front Public Health
Martín Moreno V, Pérez Rico E, Martín Fernández A, Hurtado Gallar J, Sánchez González I, Sánchez Rodríguez E, Martínez Sanz MI, Fernández Gallardo M, Marcos Guerra J, Cubero Sobrados MDC, Flórez Busto L, García Mateos A, Alonso Serna B, Vásquez Alay AL.   +13 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1.

Blood, 1995
L. Chesler, D. Golde, N. Bersch, Johnson
semanticscholar   +1 more source

Chain mediation analysis of fall risk and independent living skills in patients with acute ischemic stroke between cognitive dysfunction and frailty. [PDF]

Medicine (Baltimore)
Yang J, Liu S, He Y, Zhang Y, Niu Y, Sun H, Tai J, Zhao Z, Cui W, Yin Y, Li K, Sun H.   +11 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts

Journal of Virology, 1995
J. F. Cavender, A. Conn, M. Epler, H. Lacko, M. J. Tevethia   +4 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The human papillomavirus E6 oncogene dysregulates the cell cycle and contributes to cervical carcinogenesis through two independent activities.

Cancer Research, 2007
Anny Shai, T. Brake, C. Somoza, P. Lambert   +3 more
semanticscholar   +1 more source