Results 91 to 100 of about 7,428 (262)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Further results on outer independent triple Roman domination
AKCE International Journal of Graphs and CombinatoricsAn outer-independent triple Roman dominating function (OI[3]RDF) on a graph [Formula: see text] is function [Formula: see text] having the property that (i) if [Formula: see text] then v must have either a neighbor assigned 4 or two neighbors one of ...
F. Najafi +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
On Equality and Strong Equality of Domination Number and Independent Domination Number in Graphs
Mapana - Journal of Sciences, 2015 In this paper we explore graphs having same domination number and independent domination number . Such graphs are denoted as ( , )-graphs. Several families of ( , )-graphs have been constructed. The realization problem for graphs with = = a for any given positive integer a has been solved. Furthermore, properties of graphs in which every -set is a
Pious Femlin, Joseph Mayamma
openaire +2 more sources
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015 Let G = (V;E) be a graph. A set S ⊂ V (G) is a hop dominating set of G if for every v ∈ V - S, there exists u ∈ S such that d(u; v) = 2. The minimum cardinality of a hop dominating set of G is called a hop domination number of G and is denoted by γh(G ...
Natarajan C., Ayyaswamy S.K.
doaj +1 more source
Independent Roman Domination Stable and Vertex-Critical Graphs
IEEE Access, 2018 A Roman dominating function (RDF) on a graph $G$ is a function $f: V(G) \rightarrow \{0, 1, 2\}$ for which every vertex assigned 0 is adjacent to a vertex assigned 2. The weight of an RDF is the value $\omega (f) = \sum _{u \in V(G)}f(u)$ .
Pu Wu +5 more
doaj +1 more source
On the ratio of the domination number and the independent domination number in graphs
Discrete Applied Mathematics, 2014 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Furuya, Michitaka +2 more
openaire +1 more source