Results 41 to 50 of about 8,253 (248)
A note on cops and robbers, independence number, domination number and diameter
Discrete Mathematics, 2023 We study relations between diameter $D(G)$, domination number $γ(G)$, independence number $α(G)$ and cop number $c(G)$ of a connected graph $G$, showing (i.) $c(G) \leq α(G)-\lfloor \frac{D(G)-3}{2} \rfloor$, and (ii.) $c(G) \leq γ(G) - \frac{D(G)}{3} + O (\sqrt{D(G)})$.
Jan Petr, Julien Portier, Leo Versteegen
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
The ratio of domination and independent domination numbers on trees
, 2016 Accepted by Congressus Numernatium(2016)
Wang, Shaohui, Wei, Bing
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On average lower independence and domination numbers in graphs
Discrete Mathematics, 2005 Let \(V(G)\) be the vertex set of a graph \(G\). The lower independence number \(i_{av}(G)\) of a graph \(G\) is defined as \(\frac{1}{| V(G)| }\sum_{v\in V(G)}i_v(G)\), and the average lower domination number \({\gamma}_{av}(G)\) is defined as \(\frac{1}{| V(G)| }\sum_{v\in V(G)}{\gamma}_v(G)\), where \(i_v(G)\) is the minimum cardinality of a maximal
Blidia, Mostafa +2 more
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