Results 71 to 80 of about 7,428 (262)

Independent Dominator Sequence Number of a Graph

Procedia Computer Science, 2015
AbstractLet G = (V, E) be a connected graph. A dominator sequence in G is a sequence of vertices S = (v1, v2,. . ., vk) such that for each i with 2 ≤ i ≤ k, the vertex vi dominates at least one vertex which is not dominated by v1, v2,. . ., vi−1. If further the set of vertices in S is an independent set, then S is called an independent dominator ...
Arumugam, S., Jayaram, B., Thulasiraman, K.   +2 more
openaire   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Strong Domination Index in Fuzzy Graphs

Fuzzy Information and Engineering
In this article, a novel idea of domination degree and index are defined in a fuzzy graph (FG) using weight of strong edges. The strong domination degree (SDD) of a vertex u is defined using the weight of minimal strong dominating set (MSDS) containing u.
Kavya R. Nair, Muraleedharan Shetty Sunitha   +1 more
doaj   +1 more source

Graphs with equal domination and independent domination number

, 2015
A set S of vertices of a graph G is an independent dominating set of G if S is an independent set and every vertex not in S is adjacent to a vertex in S. The independent domination number of G, denoted by i(G), is the minimum cardinality of an independent dominating set of G.
VAİDYA, S. K., PANDİT, R. M.
openaire   +2 more sources

The ratio of domination and independent domination numbers on trees

, 2016
Let $ (G)$ and $i(G)$ be the domination number and the independent domination number of $G$, respectively. In 1977, Hedetniemi and Mitchell began with the comparison of of $i(G)$ and $ (G)$ and recently Rad and Volkmann posted a conjecture that $i(G)/ (G) \leq (G)/2$, where $ (G)$ is the maximum degree of $G$.
Wang, Shaohui, Wei, Bing
openaire   +3 more sources

Domination and independence subdivision numbers of graphs

Discussiones Mathematicae Graph Theory, 2000
A subset \(S\) of the vertex set \(V(G)\) of a graph \(G\) is called dominating in \(G\), if each vertex of \(G\) either is in \(S\), or is adjacent to a vertex of \(S\). A set \(S\subseteq V(G)\) is independent in \(G\), if no two vertices of \(S\) are adjacent in \(G\).
Haynes, Teresa W., Hedetniemi, Sandra M., Hedetniemi, Stephen T.   +2 more
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Extremal connected graphs for independent domination number

Discrete Mathematics, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Brigham, Robert C., Carrington, Julie R., Vitray, Richard P.   +2 more
openaire   +3 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source