Results 91 to 100 of about 6,849,687 (305)

What and Who Are “Essential”? A Disability Justice Perspective on COVID-19 Measures and the Diverse Disability Communities in Ontario

Studies in Social Justice
Central to Ontario’s COVID-19 response was defining, supporting, and protecting essential services and, by extension, essential people – often through decision-making processes that were ad hoc and lacking in meaningful public engagement.
Chavon Ann Niles, Mary Jean Hande, Ann Fudge Schormans , Wendy Porch, Susan Mahipaul, Jheanelle Anderson, Karen Yoshida   +6 more
doaj   +1 more source

Using Embedded Sensors in Independent Living to Predict Gait Changes and Falls

Western Journal of Nursing Research, 2016
This study explored using Big Data, totaling 66 terabytes over 10 years, captured from sensor systems installed in independent living apartments to predict falls from pre-fall changes in residents’ Kinect-recorded gait parameters.
L. Phillips, C. Deroche, M. Rantz, G. Alexander, M. Skubic, Laurel A. Despins, C. Abbott, Bradford H. Harris, C. Galambos, R. Koopman   +9 more
semanticscholar   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Increased 1-year survival and discharge to independent living in overweight hip fracture patients

Acta Orthopaedica, 2016
Background and purpose — Hip fracture patients usually have low body mass index (BMI), and suffer further postoperative catabolism. How BMI relates to outcome in relatively healthy hip fracture patients is not well investigated.
L. Flodin, Agnes Laurin, J. Lökk, T. Cederholm, M. Hedström   +4 more
semanticscholar   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Navigating new normals: the influence of COVID-19 policies on community access and well-being of people with mobility disabilities in everyday life

Frontiers in Public Health
ContextThis study explores the influence of COVID-19 public health mandates on people with mobility disabilities in the United States in their everyday lives.
Carrie L. Wendel, Randi Christine Gray, Kelsey Goddard, Jean P. Hall   +3 more
doaj   +1 more source

Effects of Video Prompting and Activity Schedules on the Acquisition of Independent Living Skills of Students Who Are Deaf and Have Developmental Disabilities

Education and Training in Autism and Developmental Disabilities, 2016
The current study investigated whether four Deaf students with developmental disabilities could learn a chain of independent living skills and follow activity schedules using a combination of the two iPod Touch applications (apps): inPromptu and First ...
Pei-Fang Wu, Joe E. Wheaton, Helen I. Cannella-Malone   +2 more
semanticscholar   +1 more source