Results 101 to 110 of about 3,030,309 (307)

Correction to: Self-managed occupational therapy and physiotherapy for adults receiving inpatient rehabilitation (‘My Therapy’): protocol for a stepped-wedge cluster randomised trial

BMC Health Services Research, 2021
Natasha K. Brusco, Christina L. Ekegren, Nicholas F. Taylor, Keith D. Hill, Annemarie L. Lee, Lisa Somerville, Natasha A. Lannin, Derick Wade, Rania Abdelmotaleb, Libby Callaway, Sara L. Whittaker, Meg E. Morris   +11 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

‘Changing the Focus’: Co-Design of a Novel Approach for Engaging People with Dementia in Physical Activity

Nursing Reports
Background: Promoting physical activity among people living with dementia is critical to maximise physical, cognitive and social benefits; yet the lack of knowledge, skills and confidence among health professionals, informal care partners and people with
Claudia Meyer, Den-Ching A. Lee, Michele Callisaya, Morag E. Taylor, Katherine Lawler, Pazit Levinger, Susan Hunter, Dawn C. Mackey, Elissa Burton, Natasha Brusco, Terry Haines, Christina L. Ekegren, Amelia Crabtree, Keith D. Hill   +13 more
doaj   +1 more source

Prevalence of nutrition risk and associated social risk factors in community living older adults in the New Zealand Health, Work and Retirement Study : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Nutrition and Dietetics at Massey University, Auckland, New Zealand [PDF]

, 2017
Background: The New Zealand population is ageing as a result of declining mortality and birth rates. In order for older adults to remain in optimal health, good nutrition is vital.
Tkatch, Melaney Tema
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Independent Living and the family: the context of Costa Rica and Sweden [PDF]

, 1994
[Excerpt] Independent Living is a philosophy and a movement of people with disabilities that works for equal opportunities, self-respect and self-determination.
Ratzka, Adolf
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pervasive Technologies and Support for Independent Living

A broad range of pervasive technologies are used in many domains, including healthcare: however, there appears to be little work examining the role of such technologies in the home, or the different wants and needs of elderly users.
Hooper, Clare
core  

Policy Options for Assisting Child SSI Recipients in Transition [PDF]

, 2003
The transition process for a child Supplemental Security Income (SSI) recipient nearing the age of 18 can be quite complicated. From a programmatic standpoint, all child SSI recipients have their eligibility redetermined under the adult SSI disability ...
David Wittenburg, Pamela J. Loprest
core