Results 71 to 80 of about 6,147,251 (299)

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Idaho State Independent Living Council 2006 Annual Report

, 2006
Idaho State Independent Living Council annual report for ...
State Independent Living Council (SILC), Idaho;
core  

Defining the meaning of independent living among persons with intellectual disabilities: a systematic literature review

, 2022
Independent living is one movement that enables people with disabilities to exercise choice and control over their lives and make all decisions regarding their own lives.
Sutan, Rosnah, Ahmad Badayai, Abdul Rahman, Amin, Aizan Sofia, Mohd Zambri, Insyirah, Mohd Kamil, Nur Khaleeda, Wan Abdullah, Wan Arnidawati, Md Akhir, Noremy, Khairuddin, Khairul Farhah   +7 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Navigating new normals: the influence of COVID-19 policies on community access and well-being of people with mobility disabilities in everyday life

Frontiers in Public Health
ContextThis study explores the influence of COVID-19 public health mandates on people with mobility disabilities in the United States in their everyday lives.
Carrie L. Wendel, Randi Christine Gray, Kelsey Goddard, Jean P. Hall   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Independent Living Unit Project: Evaluating a compact, transitional, independent living housing model for homeless men

, 2023
The Independent Living Unit Project: Evaluating a compact, transitional, independent living housing model for homeless ...
Richard Tucker (13092063), Ben Vecchiet (16752246), Fiona Andrews (13201380), David Giles (13066809), Anahita Sal Moslehian (13058286)   +4 more
core   +1 more source

The roadmap for creating a novel outdoor activity space in a rehabilitation hospital setting: the OASIS program initiative

Archives of Public Health
Introduction To meet older people's physical and mental health needs the built environment is becoming increasingly important for the health and community aged care systems.
Pazit Levinger, Jill Hall, Keith D Hill
doaj   +1 more source

Functional independence of Taiwanese patients with mucopolysaccharidoses

Molecular Genetics & Genomic Medicine, 2019
Background Information on functional strengths and weaknesses of mucopolysaccharidosis (MPS) patients is important for early intervention programs and enzyme replacement therapy (ERT).
Chung‐Lin Lee, Hsiang‐Yu Lin, Chih‐Kuang Chuang, Huei‐Ching Chiu, Ru‐Yi Tu, You‐Hsin Huang, Wuh‐Liang Hwu, Fuu‐Jen Tsai, Pao‐Chin Chiu, Dau‐Ming Niu, Yann‐Jang Chen, Mei‐Chyn Chao, Tung‐Ming Chang, Ju‐Li Lin, Chia‐Ying Chang, Yu‐Chia Kao, Shuan‐Pei Lin   +16 more
doaj   +1 more source