Results 31 to 40 of about 770 (134)

Frequency and Implications of High-Risk Pharmacogenomic Phenotypes Identified in a Diverse Australian Pediatric Oncology Cohort. [PDF]

Clin Transl Sci
ABSTRACT Pharmacogenomics remains underutilized in pediatric oncology, despite the existence of evidence‐based guidelines. Implementation of pharmacogenomics‐informed prescribing could improve medication safety and efficacy in pediatric oncology patients, who are at high risk of adverse drug reactions.
Moore C, Halman A, Stenta T, Khatri D, Williams E, Dyas R, Stolper J, Elliott DA, Conyers R.   +8 more
europepmc   +2 more sources

CURRENT THERAPIES PRIMARY LANGERHANS CELL HYSTIOCYTOSIS

Hematology, Transfusion and Cell Therapy, 2023
Langerhans cell histiocytosis (LCH) is a neoplastic histiocytic disorder that most commonly affects bones and skin, but it can also involve the bone marrow, liver, spleen, lungs, pituitary gland/central nervous system, and other organs.
Deniz Tuğcu
doaj  

An Unusual Case of Cutaneous Langerhans Cell Sarcoma Lacking S100 Expression: A Case Report and Review of the Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Langerhans cell sarcoma (LCS) is a rare neoplastic proliferation of Langerhans cell with aggressive clinical behavior and involves multiple organ systems, including the skin. LCS is characterized by marked cytologic atypia, frequent mitoses including atypical ones, and expression of CD1a, S100, and langerin (CD207).
Randa Obid, Austin R. Green, Sion W. Jasmine, Rachel P. Kowal, Brooj Abro, Laura M. Warmke, Magdalena B. Czader, Ahmed K. Alomari, Carina A. Dehner   +8 more
wiley   +1 more source

Morphological, immunohistochemical and molecular analysis of follicular dendritic cell sarcomas: L1CAM as a new diagnostic marker

Histopathology, EarlyView.
Pathohistological analysis of FDCS revealed a morphological spectrum and led to the identification of the adhesion molecule L1CAM as a novel diagnostic immunomarker for FDCS. Sequencing identified NFKBIA as the most frequently altered gene, of note, exclusively in cases with a predominant epithelioid cytomorphology.
Selina Schelbert, Katja Maurus, Sabine Roth, German Ott, Katrin S Kurz, Carolin Mogler, Barbara Wollenberg, John Linde, Alberto Zamo, Ioannis Anagnostopoulos, Susanne Gramlich, Andreas Rosenwald, Elena Gerhard‐Hartmann   +12 more
wiley   +1 more source

Novel report of an osteogenic tumor in a late Jurassic Mamenchisaurid from Thailand

Journal of Anatomy, EarlyView.
Here we describe a pathology in an ulna of a Late Jurassic mamenchisaurid from Thailand. We use anatomical descriptions, CT scanning, and bone histology to identify the pathology as an osteogenic tumor. Abstract Here we report on an osseous abnormality and multiple fractures in an ulna of a subadult basal Eusauropod (Mamenchisauridae) from the Late ...
Siripat Kaikaew, Suravech Suteethorn, Anusuya Chinsamy   +2 more
wiley   +1 more source

Application of Human Papillomavirus‐DNA Test on Salivary Gland Fine Needle Aspiration Cytology Samples Confirms the Absence of the Virus in Primary Neoplasms and Demonstrates for the First Time Its Presence in Salivary Intraglandular Cysts

Diagnostic Cytopathology, Volume 53, Issue 3, Page 127-135, March 2025.
ABSTRACT Background The correlation between Human Papillomavirus (HPV) and salivary gland neoplasms is still controversial. Data in the literature are conflicting, reporting the presence of the HPV‐DNA in a significant percentage of cases or none. We investigated the presence of HPV in a series of salivary gland neoplasms using fine needle aspiration ...
Immacolata Cozzolino, Andrea Ronchi, Marco Montella, Raffaella Ruggiero, Rosaria Cappiello, Giovanni Savarese, Giuseppe Colella, Renato Franco   +7 more
wiley   +1 more source

Features of gastrointestinal acute graft‐versus‐host disease in children undergoing hematopoietic stem cell transplantation

Journal of Pediatric Gastroenterology and Nutrition, Volume 80, Issue 2, Page 271-281, February 2025.
Abstract Objectives Graft‐versus‐host disease (GVHD) commonly affects the gastrointestinal (GI) tract among children who undergo hematopoietic stem cell transplantation (HSCT). Studies concerning GI‐acute GVHD (aGVHD) in developing countries are limited.
Kritiya Rattanaseksan, Usanarat Anurathapan, Pornthep Tanpowpong   +2 more
wiley   +1 more source

Indeterminate Cell Histiocytosis in a Pediatric Patient: Successful Treatment with Thalidomide

Pathology & Oncology Research, 2011
The 15-year-old male patient presented several 2-6 mm large livid reddish-yellowish, shiny, compact papules on the head, trunk and extremities, which had developed within the last 4 months. Histology showed normal epidermis with dense dermal infiltrate of histiocytes accompanied by few eosinophils, Touton or foamy giant cells. The histiocytes were S100
Mária Katona, Judit Hársing, Sarolta Kárpáti, Sarolta Kárpáti, Béla E. Tóth, Ágota Szepesi   +5 more
openaire   +3 more sources

Diffuse plane xanthomas as the first manifestation of multiple myeloma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Eleni Koutra, Elke Lusmöller, Hosam Ghanem, Astrid Aumann, Jens Atzpodien, Rudolf Stadler   +5 more
wiley   +1 more source

Cutaneous Rosai–Dorfman disease with MAP2K1 mutation, initially mimicking an infection with parasitized histiocytes

Journal of Cutaneous Pathology, Volume 51, Issue 12, Page 942-947, December 2024.
Abstract Rarely, Rosai–Dorfman disease (RDD) manifests exclusively in the skin, typically as nodules on the trunk and extremities. Recognition of characteristic histopathologic features enables diagnosis of RDD. A 55‐year‐old female presented with a 7‐year history of cutaneous nodules involving the trunk and extremities. A prior skin biopsy specimen at
Joseph Gillam, Ruchi Desai, Raphael J. Louie, Scott A. Turner, Grace Y. Wang, Julio A. Diaz‐Perez, Mark C. Mochel   +6 more
wiley   +1 more source