Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration. [PDF]
In Omenn syndrome, altered dendritic cell distribution and impaired migration represent an additional level of immune dysregulation, contributing to the pathogenesis of autoimmunity. OS is a severe combined immunodeficiency characterized by erythrodermia
Anselmo A +10 more
core +1 more source
A Diagnostic Mimic of Lung Cancer: Nodular Pulmonary Amyloidosis Presenting With Cystic Changes. [PDF]
A 62‐year‐old man with coal workers' pneumoconiosis and a heavy smoking history presented with progressive respiratory symptoms and cystic lung lesions. Surgical biopsy revealed localised AL (kappa) nodular pulmonary amyloidosis, highlighting the need to consider amyloidosis in the differential diagnosis of cystic lung disease with indeterminate ...
Peshin S +6 more
europepmc +2 more sources
Multiple brownish macules on child's cheeks. [PDF]
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Calogero Pagliarello +2 more
core +1 more source
Demographics and additional haematologic cancers of patients with histiocytic/dendritic cell neoplasms [PDF]
Aims: The discovery of somatic genetic alterations established many histiocytic disorders as haematologic neoplasms. We aimed to investigate the demographic characteristics and additional haematologic cancers of patients diagnosed with histiocytic ...
Bruggink, Annette H. +11 more
core +4 more sources
Solitary Type of Congenital Self-healing Reticulohistiocytosis [PDF]
Congenital self-healing reticulohistiocytosis is a rare, congenital, benign, self-healing variant of Langerhans cell histiocytosis. It usually appears as multiple papules or nodules; however, occurrence of the solitary type is very rare.
Berger +23 more
core +2 more sources
The Concise Guide to PHARMACOLOGY 2025/26: Transporters
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +28 more
wiley +1 more source
Clinical advances in musculoskeletal imaging: spondylodiscitis and pediatric oncology [PDF]
This thesis focused on two subjects in the field of musculoskeletal imaging: spondylodiscitis and bone tumors in children. Clinical imaging data were analyzed and correlated with patient characteristics, laboratory values, pathological results, and ...
Kasalak, Ömer
core +4 more sources
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis +9 more
wiley +1 more source
PET-CT-guided interventions in the management of FDG-positive lesions in patients suffering from solid malignancies: initial experiences [PDF]
Positron emission tomography-computed tomography (PET-CT) has gained widespread acceptance as a staging investigation in the diagnostic workup of malignant tumours and may be used to visualize metabolic changes before the evolution of morphological ...
Guevara, Carlos +5 more
core
Pulmonary langerhans cell histiocytosis [PDF]
Pulmonary Langerhans Cell Histiocytosis (PLCH) is a relatively uncommon lung disease that generally, but not invariably, occurs in cigarette smokers. The pathologic hallmark of PLCH is the accumulation of Langerhans and other inflammatory cells in small ...
Nowakowski, Gregorz S +3 more
core +3 more sources

