Results 51 to 60 of about 174,209,824 (205)

Coronary flow reserve and index of microcirculatory resistance in Control and MSC animals.

, 2015
1 Coronary flow reserve2 Index of microcirculatory resistance.Means and standard deviation, differences assessed with Student's t-test for independent variables (n = 9).
Eunice Oliveira (815504), Cláudia L. da Silva (141035), Sandra Cavaco-Gonçalves (815501), Nuno Cardim (815506), António Fiarresga (815499), Belmira Carrapiço (815505), Rui Cruz Ferreira (815507), Mafalda Selas (815502), Márcia F. Mata (815500), Irina N. Simões (815503), Joaquim M. S. Cabral (141046)   +10 more
core   +1 more source

Intracoronary Delivery of Human Mesenchymal/Stromal Stem Cells: Insights from Coronary Microcirculation Invasive Assessment in a Swine Model. [PDF]

PLoS ONE, 2015
Mesenchymal stem/stromal cells have unique properties favorable to their use in clinical practice and have been studied for cardiac repair. However, these cells are larger than coronary microvessels and there is controversy about the risk of embolization
António Fiarresga, Márcia F Mata, Sandra Cavaco-Gonçalves, Mafalda Selas, Irina N Simões, Eunice Oliveira, Belmira Carrapiço, Nuno Cardim, Joaquim M S Cabral, Rui Cruz Ferreira, Cláudia L da Silva   +10 more
doaj   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Effect of microcirculatory dysfunction on coronary hemodynamics:A pilot study based on computational fluid dynamics simulation [PDF]

, 2022
Background: Invasively measured fractional flow reserve (FFR) and index of microcirculatory resistance (IMR) are gold standards for the diagnosis of coronary artery disease (CAD) and coronary microcirculatory dysfunction (CMD).
Xia, Ling, Liu, Haipeng; id_orcid, Gong, Yinglan, Wang, Xinhong, Geng, Yingyi, Zhang, Jucheng, Zheng, Dingchang; id_orcid, Jiang, Jun, Jucheng Zhang, Jun Jiang, Yinglan Gong, Haipeng Liu, Dingchang Zheng, Yingyi Geng, Xinhong Wang, Ling Xia   +15 more
core   +1 more source

Feasibility and Improved Diagnostic Yield of Intracoronary Adenosine to Assess Microvascular Dysfunction With Bolus Thermodilution

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Bolus thermodilution and intravenous adenosine are established methods for coronary microcirculatory assessment. Yet, its adoption remains low, partly due to procedural time and patient discomfort associated with intravenous adenosine.
Hernan Mejia‐Renteria, Asad Shabbir, Ivan J. Nuñez‐Gil, Fernando Macaya, Pablo Salinas, Gabriela Tirado‐Conte, Luis Nombela‐Franco, Pilar Jimenez‐Quevedo, Nieves Gonzalo, Antonio Fernandez‐Ortiz, Javier Escaned   +10 more
doaj   +1 more source

Coronary Microcirculation Downstream Non‐Infarct‐Related Arteries in the Subacute Phase of Myocardial Infarction: Implications for Physiology‐Guided Revascularization

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Concerns exist about reliability of pressure‐wire‐guided coronary revascularization of non‐infarct‐related arteries (non‐IRA). We investigated whether physiological assessment of non‐IRA during the subacute phase of myocardial infarction might
Hernán Mejía‐Rentería, Joo Myung Lee, Nina W. van der Hoeven, Nieves Gonzalo, Pilar Jiménez‐Quevedo, Luis Nombela‐Franco, Iván J. Núñez‐Gil, Pablo Salinas, María Del Trigo, Enrico Cerrato, Niels van Royen, Paul Knaapen, Bon‐Kwon Koo, Carlos Macaya, Antonio Fernández‐Ortiz, Javier Escaned   +15 more
doaj   +1 more source

Remote Ischemic Post‐Conditioning Preserves the Neurovascular Unit by Brain‐Derived Gas6 That Drives Monocyte‐Derived Macrophage Reprogramming via Axl and Vimentin after SAH

Advanced Science, EarlyView.
Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu, Zichao Huang, Xi Rong, Xingwei Lei, Fuming Liang, Xiaoguo Li, Jiru Zhou, Yu Wang, Yifan Huang, Shuang Tang, Jianjun Zhong, Jin Yan, Hongji Deng, Chun Zeng, Zongduo Guo   +14 more
wiley   +1 more source

Invasive Assessment of Coronary Microcirculation: A State-of-the-Art Review

Diagnostics, 2023
A significant proportion of patients presenting with signs and symptoms of myocardial ischemia have no “significant” epicardial disease; thereby, the assessment of coronary microcirculation gained an important role in improving diagnosis and guiding ...
Luca Ciaramella, Luigi Di Serafino, Lucia Mitrano, Maria Luisa De Rosa, Carlo Carbone, Francesco Saverio Rea, Salvatore Monaco, Maria Scalamogna, Plinio Cirillo, Giovanni Esposito   +9 more
doaj   +1 more source

Posterosuperior and Anterior Rotator Cuff Repairs Yield Comparable 1‐Year Constant Scores in Routine Clinical Practice: A Propensity Score‐Matched Study From LaTour Group

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare clinical outcomes and ultrasound‐assessed healing rates between posterosuperior and anterior rotator cuff repairs using propensity score matching. Methods Consecutive patients undergoing rotator cuff repair between 2015 and 2021 by a single fellowship‐trained shoulder surgeon were included if they had posterosuperior or anterior ...
Mustafa S. Rashid, Hugo Bothorel, Alberto Guizzi, Philippe Collin, Arash Amiri, Jeanni Zbinden, Alexandre Lädermann   +6 more
wiley   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source