Results 131 to 140 of about 3,250,588 (387)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Prevalence of Protozoa and Indicator Bacteria in Wastewater Irrigation Sources in Kathmandu Valley, Nepal: Cases from Kirtipur, Bhaktapur, and Madhyapur Thimi Municipalities

, 2016
Wastewater irrigation using sewage and water from polluted sources is widespread in Kathmandu Valley, Nepal. Data on the prevalence of pathogens in irrigation sources are important for assessing the health risks for both farmers and consumers.
S. Shrestha, E. Haramoto, J. Sherchand, S. Hada, S. Rajbhandari, J. Shindo   +5 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Evaluating the Stormwater Treatment Performance of AbTech Industries Smart Sponge® Plus, Landry, N [PDF]

, 2004
The ability of AbTech’s Smart Sponge® Plus to remove fecal-borne bacteria from stormwater was evaluated in a storm drainage system located in Seabrook, New Hampshire.
Jones, Stephen H., Landry, Natalie, Nolan, Scott   +2 more
core   +1 more source

The Effect of Microcystis on the Monitoring of Faecal Indicator Bacteria. [PDF]

Toxins (Basel), 2023
Zhou J, Qu M, Dunkinson C, Lefebvre DD, Wang Y, Brown RS.   +5 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Distribution of Genetic Marker Concentrations for Fecal Indicator Bacteria in Sewage and Animal Feces [PDF]

, 2012
Catherine A. Kelty, Manju Varma, Mano Sivaganesan, Richard A. Haugland, Orin C. Shanks   +4 more
openalex   +1 more source

Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2020/2021 – Ireland

, 2023
The Food Safety Authority Of Ireland
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source