Results 121 to 130 of about 2,686,565 (303)
Citation: 'indirect ecological effect' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14757 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Indirect Costs and Cost-Effectiveness Analysis
Value in Health, 2006 This article examines the methodological implications of the societal perspective in cost-effectiveness analyses in which the costs of health-care interventions are defined as the sums of direct and indirect costs. In the model of cost-effectiveness analysis in which the planner distributes patients among many treatments for many illnesses, the ...
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Demographic Research, 2005 Several methods were proposed to decompose the difference between two life expectancies at birth into the contribution by different age groups. In this study an attempt has been made to compare different methods with that of Chandra Sekar (1949) method ...
P. K. Murthy
doaj
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Job satisfaction and the individual educational level, re-assessing their relationship [PDF]
We examine the factors that shape job satisfaction and in particular, the direct and indirect effects of the educational level. Our motivation is based on extending a large body of researches that is focused on private sector data by employing a larger ...
Marisa Bucheli +3 more
core
Gender analysis of the changes in indirect taxes introduced by the coalition government, 2010-2011 [PDF]
, 2011 On behalf of the WBG, Jerome De Henau and Cristina Santos have produced an examination of the UK government's main changes in indirect taxes from a gender perspective.
de Henau, Jerome, Santos, Cristina
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source