Results 101 to 110 of about 2,702,302 (307)

Cognitive appraisals, emotional reactions, and their associations with three forms of peer-victimization [PDF]

open access: yes, 2012
Victimized students’ cognitive appraisals (perceived threat, control) are related to emotional reactions. Furthermore, psychosocial wellbeing is differentially associated with form of victimization (direct vs.
Anderson, Shayron, Hunter, Simon C.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

EFFECTIVENESS OF EU LAW IN MEMBER STATES [PDF]

open access: yesChallenges of the Knowledge Society, 2011
When the original Rome Treaty was drafted, it was envisaged by the authors that the procedure as set out in what is now article 258 T.F.E.U. (infringement procedure) would be the primary means by which EU law is enforced - a “centralized” and “public ...
ANCA-MAGDA VLAICU
doaj  

medflex: An R Package for Flexible Mediation Analysis using Natural Effect Models

open access: yesJournal of Statistical Software, 2017
Mediation analysis is routinely adopted by researchers from a wide range of applied disciplines as a statistical tool to disentangle the causal pathways by which an exposure or treatment affects an outcome.
Johan Steen   +3 more
doaj   +1 more source

Indirect effects between deer, mice, and the gypsy moth in a forest community [PDF]

open access: yes, 2014
White-tailed deer are ecosystem engineers that dramatically alter forest understory vegetation. Consequently, deer can impact many species in a forest through both direct and indirect effects. One species that deer may indirectly affect is the gypsy moth,
Wojcikiewicz, John
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Indirect Effects of Universal Infant Rotavirus Vaccination: A Narrative Systematic Review

open access: yesVaccines
Background/Objective: Rotavirus is a major cause of acute gastroenteritis (AGE) in children
Darren Suryawijaya Ong   +3 more
doaj   +1 more source

The Effects of Dividend Policy On the Price of Shares of Microfinance Companies In Developing Countries [PDF]

open access: yesSocioEconomic Challenges
The strategy of dividend policy implementation in the context of business value growth is the subject of debates in theoretical and empirical research.
Prem Bahadur Budhathoki, Kumar Khadka
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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