Results 91 to 100 of about 2,702,302 (307)
Direct and Indirect Effects of Public Infrastructure on Regional Economic Growth in Japan: An Application of the Covariance Structure Model by Geographical Classification Area [PDF]
The direct and indirect effects of public infrastructure (PI) were evaluated by a covariance structure model. Empirical results showed the positive indirect effect, crowding-in effect, as well as the direct effect as an input factor, differences of these
Kunimitsu, Yoji
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Indirect Tax Reform in the Philippines: A Complementary Measure to the Tariff Reform Program, 1979-1985 [PDF]
This study analyzes the effect of the interaction between domestic indirect taxes and tariff system to the market of particular goods. Computation of effective protection rates is provided and the implications of alternative indirect tax schemes are ...
Manasan, Rosario G.
core +2 more sources
Вестник СибАДИ, 2017 The authors present an analysis of the energy audit of the holding company “Russian Railways”, as the main tool to assess the effectiveness of consumption of fuel and energy resources in the operation of facilities and logistics infrastructure of railway
R. S. Simak, R. S. Sattarov
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Threshold levels and the realization of a group benefit [PDF]
This paper considers a voluntary contribution threshold game in which a group benefit is realized only if the number of contributors at least reaches a threshold level, and analyzes the effect of the threshold level on the likelihood that the group ...
Xiaopeng Xu
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Frontiers in PsychologyIntroductionThis study aims to investigate whether exercise adherence and positive mental character significantly affect subjective well-being among Chinese college students during the COVID-19 pandemic and whether positive mental character plays a ...
Yonghuan Chen +5 more
doaj +1 more source
Geophysical Research Letters, 2020 Clouds and their response to aerosols constitute the largest uncertainty in our understanding of 20th‐century climate change. We present an investigation that determines linkages between remotely sensed marine cloud properties with in situ measurements ...
Kenneth Sinclair +6 more
doaj +1 more source
On the links between employment, partnership quality, and the desire to have a first child [PDF]
We examine the impact of precarious work (low income and job security satisfaction) on the intention to have a first child. We consider a direct and an indirect effect; the latter is mediated by partners’ conflict behaviour, conflict level, and ...
Bernd Weiß +2 more
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