Results 61 to 70 of about 968,367 (316)

On relation between separable indirect effect, natural indirect effect, and interventional indirect effect

open access: yes
Recently, the separable indirect effect (SIE) has gained attention due to its identifiability without requiring the untestable cross-world assumption necessary for the natural indirect effect (NIE). This article systematically compares the causal assumptions underlying the SIE, NIE, and interventional indirect effect (IIE) and evaluates their ...
Chen, Yan-Lin, Lin, Sheng-Hsuan
openaire   +2 more sources

The ‘Indirect’ Effects of Cytomegalovirus Infection

open access: yesAmerican Journal of Transplantation, 2009
Cytomegalovirus (CMV) remains the most important infection in the immunocompromized host even in the era of effective therapy. CMV is usually acquired early in life and can be transmitted by contact with infected body fluids. In the immunocompetent population, primary infection is almost always of little clinical consequence.
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

PATH ANALYSIS OF FACTORS INFLUENCING CASHLESS SOCIETY DEVELOPMENT USING BOOTSTRAP RESAMPLING

open access: yesBarekeng
Path analysis can be applied to various fields, one of which is the field of banking economics. This study is aimed to examine what factors significantly affect the development of cashless society both directly and indirectly.
Dea Saraswati Pramaningrum   +3 more
doaj   +1 more source

Bootstrap Model-Based Constrained Optimization Tests of Indirect Effects

open access: yesFrontiers in Psychology, 2020
In mediation analysis, conditions necessary for commonly recommended tests, including the confidence interval (CI)-based tests, to produce an accurate Type I error, do not generally hold for finite sample sizes and non-normally distributed model ...
Davood Tofighi
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Detecting cryptic indirect genetic effects.

open access: yesEvolution; international journal of organic evolution, 2014
Research supported by NERC grants NE/G014906/1 & NE/I016937/1. APC paid through RCUK OA funds.
Bailey, Nathan William   +1 more
openaire   +4 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Indirect effect.

open access: yes, 2015
*p < .05;**p < .01;***p < .001.Indirect effect.
Juan José Pulido-González (748769)   +4 more
core   +1 more source

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