Advanced Science, EarlyView.This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang +10 more
wiley +1 more source
Emotional vigilance under perceived continuous evaluation in foreign language classrooms: evidence from Chinese university students. [PDF]
Front PsycholDing Z, Bu G, Fang Q.
europepmc +1 more source
Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction
Advanced Science, EarlyView.This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng +12 more
wiley +1 more source
Serial mediation of affective domain ability and feedback-seeking behaviour in the relationship between career adaptability and transition shock among novice nursing interns: a multicentre cross-sectional study. [PDF]
BMC Med EducLei Y +5 more
europepmc +1 more source
Advanced Science, EarlyView.Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan +11 more
wiley +1 more source
How mindfulness unlocks employee creativity: the role of workplace curiosity and performance feedback. [PDF]
Front PsycholLiu X, Liu Q, Liu H.
europepmc +1 more source
Electrocatalytic Coupling Conversion of Methane by Dual‐Site Control in Nickel Oxyhydroxide
Advanced Science, EarlyView.Electrocatalytic coupling conversion of methane (CH4) is accomplished on the nickel oxyhydroxide (NiOOH), wherein the Ni─O dual‐site is triggered via the proper electronic interaction, synergistically promoting the C─H activation and C─C formation, enabling a selective and efficient C2 product generation route under ambient conditions. ABSTRACT Methane
Kailong Lu +7 more
wiley +1 more source
Comparative effectiveness of different inhaler technique education modalities on clinical outcomes in patients with asthma and chronic obstructive pulmonary disease: a protocol for a systematic review and network meta-analysis of randomised controlled trials. [PDF]
BMJ OpenYang X, Chen X, Yang C, Feng M, Wu Y.
europepmc +1 more source
Advanced Science, EarlyView.Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak +6 more
wiley +1 more source
Many studies have shown that the indirect corrective feedback has a good impact on the ESL students? written work. Therefore, the purpose of this research is to determine whether the indirect corrective feedback given by the teacher has an effect or not ...
Rizkia Mutiara Ramadhani
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