Results 71 to 80 of about 722,268 (215)

Indirect Method for Estimation of Reference Intervals of Inflammatory Markers. [PDF]

Ann Lab Med, 2023
Kang T, Yoo J, Jekarl DW, Chae H, Kim M, Park YJ, Oh EJ, Kim Y.   +7 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Reference intervals for thyroid disorders calculated by indirect method and comparison with reference change values. [PDF]

Biochem Med (Zagreb), 2023
Yildiz Z, Dağdelen LK.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Method of indirect determination of thermal load parameter

Journal of Thermal Engineering, 2019
An indirect method for determining the effectiveness of the transformers operating in a distribution network with variable load schedules, according to th e parameter of their thermal load as a ratio of heat accumulated by transformer oil to the maximum ...
Yurii BAİDAK
doaj   +1 more source

An Indirect Method for Determining the Local Heat Transfer Coefficient of Gas Flows in Pipelines. [PDF]

Sensors (Basel), 2022
Plotnikov L, Plotnikov I, Osipov L, Slednev V, Shurupov V.   +4 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

An Indirect Method of Micromagnetic Structure Estimation in Microwires. [PDF]

Nanomaterials (Basel), 2021
Alekhina I, Kolesnikova V, Rodionov V, Andreev N, Panina L, Rodionova V, Perov N.   +6 more
europepmc   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

The indirect method in the establishment of reference intervals for complement 3 and complement 4: A retrospective study. [PDF]

J Taibah Univ Med Sci, 2022
Chai J, Sun Z, Xing D, Zhou Q, Xu J.
europepmc   +1 more source