Results 51 to 60 of about 205,197 (219)

The Factor Structure of Cognitive Functioning in Cognitively Healthy Participants: a Meta-Analysis and Meta-Analysis of Individual Participant Data [PDF]

Neuropsychology Review, 2020
AbstractMany neuropsychologists are of the opinion that the multitude of cognitive tests may be grouped into a much smaller number of cognitive domains. However, there is little consensus on how many domains exist, what these domains are, nor on which cognitive tests belong to which domain.
Agelink van Rentergem, J.A., de Vent, N.R., Schmand, B.A., Murre, J.M.J., Staaks, J.P.C., Huizenga, H.M.   +5 more
openaire   +5 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Identifying relapse predictors in individual participant data with decision trees

BMC Psychiatry, 2023
Background Depression is a highly common and recurrent condition. Predicting who is at most risk of relapse or recurrence can inform clinical practice. Applying machine-learning methods to Individual Participant Data (IPD) can be promising to improve the
Lucas Böttcher, Josefien J. F. Breedvelt, Fiona C. Warren, Zindel Segal, Willem Kuyken, Claudi L. H. Bockting   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Single-gene transcripts for subclinical tuberculosis: an individual participant data meta-analysis

The Lancet Microbe
Summary: Background: Translation of blood RNA signatures might be accelerated by identifying biomarkers composed of the minimum number of gene transcripts.
James Greenan-Barrett, MRCP, Simon C Mendelsohn, PhD, ProfPhD Thomas J Scriba, PhD, ProfPhD Mahdad Noursadeghi, PhD, Rishi K Gupta, PhD   +4 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Effect of Vitamin D Supplementation on Markers of Vascular Function: A Systematic Review and Individual Participant Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundLow 25‐hydroxyvitamin D levels are associated with an increased risk of cardiovascular events, but the effect of vitamin D supplementation on markers of vascular function associated with major adverse cardiovascular events is unclear.
Louise A. Beveridge, Faisel Khan, Allan D. Struthers, Jane Armitage, Ilaria Barchetta, Iain Bressendorff, Maria Gisella Cavallo, Robert Clarke, Rinkoo Dalan, Gavin Dreyer, Adam D. Gepner, Nita G. Forouhi, Ryan A. Harris, Graham A. Hitman, Thomas Larsen, Rajesh Khadgawat, Peter Marckmann, Frank H. Mose, Stefan Pilz, Alexandra Scholze, Marina Shargorodsky, Seth I. Sokol, Hans Stricker, Carmine Zoccali, Miles D. Witham   +24 more
doaj   +1 more source

The Mortality After Release from Incarceration Consortium (MARIC): Protocol for a multi-national, individual participant data meta-analysis

International Journal of Population Data Science, 2020
Introduction More than 30 million adults are released from incarceration globally each year. Many experience complex physical and mental health problems, and are at markedly increased risk of preventable mortality.
Rohan Borschmann, Holly Tibble, Matthew J Spittal, David Preen, Jane Pirkis, Sarah Larney, David L Rosen, Jesse T Young, Alexander D Love, Frederick L Altice, Ingrid A Binswanger, Anne Bukten, Tony Butler, Zheng Chang, Chuan-Yu Chen, Thomas Clausen, Peer Brehm Christensen, Gabriel J Culbert, Louisa Degenhardt, Anja J.E. Dirkzwager, Kate Dolan, Seena Fazel, Colin Fischbacher, Margaret Giles, Lesley Graham, David Harding, Yen-Fang Huang, Florence Huber, Azar Karaminia, Fiona G Kouyoumdjian, Sungwoo Lim, Lars Møller, Akm Moniruzzaman, Jeffrey Morenoff, Eamonn O'Moore, Lia N Pizzicato, Daniel Pratt, Scott F Proescholdbell, Shabbar I Ranapurwala, Meghan E Shanahan, Jenny Shaw, Julian M Somers, Anne C Spaulding, Marc F Stern, Kendra M Viner, Nadia Wang, Melissa Willoughby, Stuart A Kinner   +47 more
doaj   +1 more source

Nifedipine maintenance tocolysis and perinatal outcome: an individual participant data meta‐analysis

BJOG: An International Journal of Obstetrics & Gynaecology, 2016
BackgroundPreterm birth is the leading cause of neonatal mortality and morbidity in developed countries. Whether continued tocolysis after 48 hours of rescue tocolysis improves neonatal outcome is unproven.ObjectivesTo evaluate the effectiveness of maintenance tocolytic therapy with oral nifedipine on the reduction of adverse neonatal outcomes and the ...
van Vliet, E. O. G., Dijkema, G. H., Schuit, E., Heida, K. Y., Roos, C., van der Post, J. A. M., Parry, E. C., McCowan, L., Lyell, D. J., El-Sayed, Y. Y., Carr, D. B., Clark, A. L., Mahdy, Z. A., Uma, M., Sayin, N. C., Varol, G. F., Mol, B. W., Oudijk, M. A.   +17 more
openaire   +4 more sources