Results 131 to 140 of about 487,159 (190)

Microbiota-derived IPA mitigates post-stroke neuroinflammation by inhibiting TREM2-dependent pyroptosis

Journal of Neuroinflammation
Ischemic stroke remains the leading cause of long-term disability globally, underscoring the urgent need for novel therapeutic strategies. Here, we explore a microbiota-gut-brain axis that provides valuable insights for achieving this objective ...
Jun-Min Chen, Cong Zhang, Lu-Lu Yu, Jian-Xu Sun, Jiang-Hao Zhang, Lu Chen, Fei Zhu, Guang Shi, Lan Yang, An-Chen Guo, Jian-Ping Wu, Tie-Shan Tang, Qun Wang   +12 more
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Hydrogen-deuterium exchange of indole-3-propionic acid with deuterated trifluoromethanesulfonic acid

Hydrogen-deuterium exchange of indole-3-propionic acid with deuterated trifluoromethanesulfonic acid
Indole-3-propionic acid (IPA), a member of the plant auxin family, plays an important role in biological activity. There are few reports on the preparation of deuterated IPA. Deuterated trifluoromethanesulfonic acid (TfOD) is a hydrogen-deuterium exchange reagent used for aromatic compounds.
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Additional file 1 of Indole-3-propionic acid promotes hepatic stellate cells inactivation

Additional file 1.
Ilha, Mariana, Sehgal, Ratika, Matilainen, Johanna, Rilla, Kirsi, Kaminska, Dorota, Gandhi, Shrey, Männistö, Ville, Ling, Charlotte, Romeo, Stefano, Pajukanta, Päivi, Pirinen, Eija, Virtanen, Kirsi A., Pietiläinen, Kirsi H., Vaittinen, Maija, Pihlajamäki, Jussi   +14 more
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Gut microbiota-derived indole-3-propionic acid alleviates endoplasmic reticulum stress by regulating FMO2 in MASLD. [PDF]

Hepatol Commun
Luo Y, Zhang Y, Zhang Q, Li X, Cai K, Xu Y, Zhao R, Zhang S, Bai X, Chen H, Li H, Hong Y, Liao Q, Xie Z.   +13 more
europepmc   +1 more source

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis. [PDF]

Int J Mol Med
Bai J, Wang R, Fan J, Su S, Si G, You Q, Sun A, Hu D, Gao S, Lv Y, Zhou F.   +10 more
europepmc   +1 more source

Melatonin and Indole-3-Propionic Acid Reduce Surface FcγRIII/CD16-Related Parameters in Porcine Peripheral Blood Mononuclear Cells In Vitro. [PDF]

Int J Mol Sci
Śliwka PW, Stępniak J, Karbownik-Lewińska M.   +2 more
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Indole-3-propionic acid suppresses prostate cancer by inducing cell cycle arrest and apoptosis associated with p53 activation. [PDF]

Front Oncol
Huang Y, Liu X, Wu Y, Li S, Shen Y, Wan H, Zhang Y, Feng N.   +7 more
europepmc   +1 more source

Pre-treatment with baicalein alleviates the diquat-induced microglial pyroptosis through gut microbiota-derived indole-3-propionic acid and DDX3X/G3BP1 pathway. [PDF]

Cell Biol Toxicol
Li T, Feng M, Wang P, Jiang M, Cui J, Jin M, Song C, Lin L, Lu YQ.   +8 more
europepmc   +1 more source

Microbiota-derived indole-3-propionic acid extends lifespan in Drosophila and improves muscle and bone health in mice. [PDF]

Geroscience
Vyavahare S, Berger F, Swint SG, Mendhe B, Shukla M, Duchesne I, Zhong R, Cooley MA, McGee-Lawrence ME, Isales CM, Hoffman JM, Fulzele S.   +11 more
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Pretreatment with Indole-3-Propionic Acid Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction and Inflammation Through the AhR/NF-κB/NLRP3 Pathway

Journal of Inflammation Research
Yiqiong Zhang,1,2,* Shanshan Li,1,2,* Xiaojuan Fan,1 Yue Wu1,2 1Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Key Laboratory of Environment and ...
Zhang Y, Li S, Fan X, Wu Y
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