Results 161 to 170 of about 487,159 (190)
Some of the next articles are maybe not open access.
Indole‐3‐propionic acid attenuates neuronal damage and oxidative stress in the ischemic hippocampus
Journal of Neuroscience Research, 2009AbstractTryptophan‐derived indole compounds have been widely investigated as antioxidants and as free‐radical scavengers. Indole‐3‐propionic acid (IPA), one of these compounds, is a deamination product of tryptophan. In the present study, we used Mongolian gerbils to investigate IPA's neuroprotective effects against ischemic damage and its ...
In Koo Hwang +2 more
exaly +3 more sources
American Journal of Clinical Nutrition, 2022
Indole-3-propionic acid (IPA), a microbiota-produced tryptophan metabolite, has been shown to exhibit cardioprotective effects in animal models. However, the relation of IPA with cardiovascular risk in humans is currently unknown.This prospective study aimed to investigate whether plasma tryptophan and IPA levels are associated with decreased risks of ...
Yiran You, Xu Wang, Yan Yang
exaly +3 more sources
Indole-3-propionic acid (IPA), a microbiota-produced tryptophan metabolite, has been shown to exhibit cardioprotective effects in animal models. However, the relation of IPA with cardiovascular risk in humans is currently unknown.This prospective study aimed to investigate whether plasma tryptophan and IPA levels are associated with decreased risks of ...
Yiran You, Xu Wang, Yan Yang
exaly +3 more sources
Acta Crystallographica Section C Crystal Structure Communications, 1998
The title compound, C 11 H 11 NO 2 , has a fully extended propionic acid side chain. The molecules are held together as dimers by centrosymmetric pairs of intermolecular hydrogen bonds between the carboxyl groups. The O...O distance is 2.649 (2) A.
N. Okabe, Y. Adachi
openaire +1 more source
The title compound, C 11 H 11 NO 2 , has a fully extended propionic acid side chain. The molecules are held together as dimers by centrosymmetric pairs of intermolecular hydrogen bonds between the carboxyl groups. The O...O distance is 2.649 (2) A.
N. Okabe, Y. Adachi
openaire +1 more source
Syntheses, structures and properties of complexes of indole-3-propionic acid
Transition Metal Chemistry, 2016Three complexes [Zn2(IPA)2(phen)4](HIPA)2(NO3)2·H2O (1), {[Zn(IPA)2(bipy)]·3H2O}n (2), and {[Mn(IPA)2(bipy)(H2O)]·2H2O}n (3) (HIPA = indole-3-propionic acid, phen = 1,10-phenanthroline, bipy = 4,4′-bipyridine) were synthesized and characterized by physico-chemical and spectroscopic methods.
Xiu-jun Deng +4 more
openaire +1 more source
Journal of Agricultural and Food Chemistry, 2020
Destruction in intestinal barrier is concomitant with the intestinal diseases. There is growing evidence that tryptophan-derived intestinal bacterial metabolites play a critical role in maintaining the balance of intestinal mucosa. In this study, the Caco-2/HT29 coculture model was used to evaluate the effect of indole-3-propionic acid (IPA) on the ...
Jiaojiao Li +5 more
openaire +2 more sources
Destruction in intestinal barrier is concomitant with the intestinal diseases. There is growing evidence that tryptophan-derived intestinal bacterial metabolites play a critical role in maintaining the balance of intestinal mucosa. In this study, the Caco-2/HT29 coculture model was used to evaluate the effect of indole-3-propionic acid (IPA) on the ...
Jiaojiao Li +5 more
openaire +2 more sources
Role of indole-3-propionic acid, a gut microbiota-derived metabolite, in endothelial dysfunction
Atherosclerosis, 2023Background and Aims: Indole-3-propionic acid (IPA) is a molecule pro- duced by the intestinal microbiota, after tryptophan ingestion. From the gut, IPA is absorbed through the intestinal barrier and enters the systemic circulation, where it plays several physiological roles, such as regulation of the intestinal barrier function, antioxidant and anti ...
Geddo, F. +5 more
openaire +2 more sources
The mechanism of action of indole-3-propionic acid on bone metabolism
Food & FunctionIPA binds to AhR and PXR receptors, regulating bone metabolic disorders.
Huimin Xu, Yingzhe Luo, Yi An, Xi Wu
openaire +2 more sources
Organic Preparations and Procedures International, 1981
(1981). TWO EFFICIENT SYNTHESES OF INDOLE-3-PROPIONIC ESTERS AND ACIDS. FURTHER APPLICATIONS OF MELDRUM'S ACID. Organic Preparations and Procedures International: Vol. 13, No. 1, pp. 39-48.
Diane S. Farlow +4 more
openaire +1 more source
(1981). TWO EFFICIENT SYNTHESES OF INDOLE-3-PROPIONIC ESTERS AND ACIDS. FURTHER APPLICATIONS OF MELDRUM'S ACID. Organic Preparations and Procedures International: Vol. 13, No. 1, pp. 39-48.
Diane S. Farlow +4 more
openaire +1 more source
International Immunopharmacology
Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease for which current therapeutic approaches still face many dilemmas, and targeting macrophage polarization and metabolism for the treatment of this disease is a potentially effective strategy.
Jiahong, Li +3 more
openaire +2 more sources
Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease for which current therapeutic approaches still face many dilemmas, and targeting macrophage polarization and metabolism for the treatment of this disease is a potentially effective strategy.
Jiahong, Li +3 more
openaire +2 more sources