Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. [PDF]
, 2018 Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and dose-limiting side effect of cancer treatment that affects millions of cancer survivors throughout the world and current treatment options are extremely limited by their side effects ...
Mackie, Ken +6 more
core +1 more source
Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]
, 2014 Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
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Genetic and phenotypic characterization of intestinal spirochetes colonizing chickens and allocation of known pathogenic isolates to three distinct genetic groups [PDF]
, 1997 Infection with intestinal spirochetes has recently been recognized as a cause of lost production in the poultry industry. Little is known about these organisms, so a collection of 56 isolates originating from chickens in commercial flocks in Australia ...
McLaren, A.J. +4 more
core +1 more source
A Hyperstable Miniprotein: Additive Effects of D- and L-Ala Substitutions [PDF]
, 2008 The effects of alanine substitutions in each helical segment of the structure, and Gly to D-Ala mutations at sites where glycines have positive phi angles in the Trp-cage miniprotein are reported.
Bipasha Barua +2 more
core +1 more source
Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling
Angewandte Chemie International Edition, EarlyView.Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl +1 more
wiley +1 more source
Sensory emphasis on pork quality related to the diet content of fermentable fibre-rich feedstuffs (chicory and lupine) with special emphasis on the effect on boar taint [PDF]
, 2007 Boar taint in entire male pork is caused by skatole and andros-tenone and other compounds such as indole. However, female pigs also pro-duce skatole and indole.
Byrne, Derek Victor +2 more
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Synthesis and D2-like binding affinity of new derivatives of N3-[(1- ethyltetrahydro-1H-2-pyrrolyl)methyl]-4,5-dihydrobenzo[g]indole-3- carboxamide and related compounds [PDF]
, 2000 In previous papers 4a,b we have reported the syntheses and structure-activity relationships of a series of 5-phenyl-3-pyrrole carboxamide and related 4,5-dihydrobenzo[g]indole-3-carboxamide analogues whose most representative terms were 1a and 2a ...
Chelucci, Giorgio Adolfo +5 more
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Formamidines with antinociceptive and antiinflammatory activities [PDF]
, 1991 Pursuing our investigations on 7-amino-2,3-polymethyleneindole derivatives, a set of 7-(dimethylaminomethylene)-amino-2,3-polymethyleneindoles, together with some other aryl or cycloalkyl substituted formamidines, were prepared and tested for analgesic ...
Boatto, Gianpiero +6 more
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