Results 181 to 190 of about 288,739 (291)

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

pH regulates gut bacterial tryptophan metabolism. [PDF]

NPJ Biofilms Microbiomes
Brinck JE, Laursen MF, Pedersen M, Carey MR, Procházková N, Jørgensen MS, Mortensen MS, Lauritzen L, Pedersen O, Roager HM, Licht TR, Sinha AK.   +11 more
europepmc   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

Enzyme-Targeted Antiproliferative Effects of Novel Indole-Acrylamide Xenobiotics Acting on Cyclooxygenase Pathways. [PDF]

J Xenobiot
Hawash M, Mahmutoğlu B, Abualhasan M, Kahraman DC, Baytas SN.   +4 more
europepmc   +1 more source

Emerging Trends in Organic Photoreactions Utilizing Disulfides

European Journal of Organic Chemistry, EarlyView.
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar, Bolormaa Bayarkhuu, Hong Y. Cho, Jeehye Byun   +3 more
wiley   +1 more source

Indole Peptidomimetics Show Potent and Selective Activity against Drug-Resistant <i>Plasmodium falciparum</i>. [PDF]

ACS Omega
Januário MAP, Valdes TA, Maluf SEC, Mendes GR, Bonatto V, Moura IMR, Mourão PS, Corrêa AG, Guido RVC.   +8 more
europepmc   +1 more source

Design and Synthesis of Lactose‐Derived Ligands and Their Application in Asymmetric Friedel–Crafts Alkylation

European Journal of Organic Chemistry, EarlyView.
This work describes the synthesis of lactose‐ and glucose‐derived chiral ligands and their application in the catalytic enantioselective Friedel–Crafts alkylation of indole with a series of trans‐β‐nitrostyrenes. The optimal ligand was an acetate protected, lactose‐derived pyridyl imine and its zinc complex afforded ees up to 93% and yields up to 93 ...
Sandra Bulawa, Julia Bruno‐Colmenarez, Patrick J. Guiry   +2 more
wiley   +1 more source

Indolyl substituted 4-oxobut-2-enoic acids. Synthesis and aza-Michael additions

Open Chemistry, 2007
Berkeš Dušan, Koren̆ová Anna, Šafár̆ Peter, Horváthová Helena, Prónayová Nadežda   +4 more
doaj   +1 more source

Electrochemically driven strain-release dearomative (3 + 2) cyclization for the synthesis of bicyclo[2.1.1]hexane-fused polycyclic spiroindolines. [PDF]

Chem Sci
Zhu Y, Pu E, Yang S, Zhao D, Xu Q, Jiang P, Li X, Zhang H, Chen J.   +8 more
europepmc   +1 more source

Hofmann Degradation of Asparagine and Glutamine as an Efficient Approach for the Synthesis of Derivatized Lysine Homologs

European Journal of Organic Chemistry, EarlyView.
A practical and scalable route to C1 and C2 lysine homologs has been developed using Hofmann degradation of N‐protected L‐asparagine and L‐glutamine as the key step. These short‐tether scaffolds enable efficient synthesis of diverse Fmoc‐protected noncanonical amino acids (ncAAs) bearing donor, acceptor, redox‐active, and fluorescent residues.
Adelaide R. Mashweu, François J. De Beer, Jolien Bertouille, Steven Ballet, Charlotte Martin, Ulrich Hennecke, Charlene Marais, Vladimir A. Azov   +7 more
wiley   +1 more source