Results 211 to 220 of about 178,765 (288)

The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of diabetes by enhancing GLP-1 secretion and L cell differentiation. [PDF]

Diabetologia
Phuah P, Norton M, Cheng S, Roberts AG, Pirri D, Meyer L, Chung PE, Dunsterville C, Karwowski R, Lam BYH, Otsubo E, Aleksashina S, Gribble FM, Reimann F, Hanyaloglu AC, Yeo GSH, Bewick GA, Jones B, Owen B, Murphy KG.   +19 more
europepmc   +1 more source

One‐Shot Pd(II)‐Catalyzed Multiple C–H Activation Enables Modular Construction of Fluorenylidene Oxindole‐Based Multi(Polycyclic) Aromatic Enes

Chemistry – A European Journal, EarlyView.
A one‐shot Pd(II)‐catalyzed C─H activation strategy enables the rapid conversion of simple linear propiolamides into structurally diverse mono‐, di‐, and tri‐olefin‐bridged MPAEs. This cascade process orchestrates up to six sequential C–H activations in a single operation, providing streamlined access to highly conjugated architectures.
Haiyu Wang, Kouki Sakata, Takuma Sato, Masahiro Terada, Tienan Jin   +4 more
wiley   +1 more source

Serum microbiome-related metabolites-including short-chain fatty acids and indole derivatives-predict outcome and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: a two-timepoint LC-MS study. [PDF]

Front Neurol
Nagybanyai-Nagy B, Tengölics R, Sajben C, Olasz D, Schwarcz A, Molnar T, Csecsei P.   +6 more
europepmc   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

Chemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal, Alexandre Millanvois, Louis Fensterbank, Cyril Ollivier   +3 more
wiley   +1 more source

Single-atom substitution redirects KatG reactivity from cofactor biogenesis to stereoselective sulfoxidation. [PDF]

Nat Commun
Duan R, Li J, Griffith WP, Xu Y, Burrows ND, Green AP, Liu A.   +6 more
europepmc   +1 more source

Nitrooxylation in Organic Synthesis: From Classical Nitrate Ester Formation to Modern Catalytic Strategies

Chemistry – A European Journal, EarlyView.
Nitrooxylation—the installation of nitrate esters (–ONO2) has evolved from classical mixed‐acid protocols to catalytic and mechano‐, flow‐, photo‐, and electrochemical strategies. This review delineates ionic and radical manifolds for C–ONO2 bond formation, emphasizing mechanistic control, selected substrate scope, and selectivity.
Jayanta Dey, Dmitry Katayev
wiley   +1 more source

Effects of the IAA-Producing Endophytic <i>Bacillus</i> spp. on the Growth of <i>Hordeum vulgare</i> L. [PDF]

Microorganisms
Güler M.
europepmc   +1 more source

A Selectfluor‐based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications

Chemistry – A European Journal, EarlyView.
Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn, Susanne Gradl, Vanessa Osterloh, Peter Gmeiner, Harald Hübner, Markus R. Heinrich   +5 more
wiley   +1 more source

TusDCB-mediated tRNA sulfur modification is required for virulence and intestinal fitness in enterohemorrhagic <i>Escherichia coli</i>. [PDF]

Infect Immun
Sato Y, Suzue K, Obinata H, Horinouchi M, Takita A, Maruhashi M, Minamishima YA, Tomita H, Hirakawa H.   +8 more
europepmc   +1 more source