Results 241 to 250 of about 329,198 (291)

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Rational design and synthesis of new acetamide-indole-benzo[d]imidazole-carboxylic acid hybrids as dual PTP1B/α-glucosidase inhibitors. [PDF]

RSC Adv
Dastyafteh N, Ghafouri SN, Mollazadeh M, Motamedi Shakib N, Halimi M, Hosseini S, Mojtabavi S, Faramarzi MA, Larijani B, Amanlou M, Mohammadi-Khanaposhtani M, Mahdavi M.   +11 more
europepmc   +1 more source

Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation

iMetaOmics, EarlyView.
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu, Zhibiao Li, Lin Yang, Jun Zheng, Weijia Li, Rulin Liao, Wenxue Huang, Boyuan Sun, Zhuohang Li, Cunzhen Ma, Xunguo Yang, Zongwei Wang, Jie Zhao, Bisheng Cheng, Peng Wu   +14 more
wiley   +1 more source

Alterations in Tryptophan Metabolism and the Indole Pathway in Colorectal Cancer Patients: A Systematic Review and Meta-analysis. [PDF]

MedComm (2020)
Griffith L, Sinha A, Acharjee A.
europepmc   +1 more source

Sustainable Carbon Source Utilization for Indole-3-Acetic Acid Production by Marine Pseudomonas fluorescens BCPBMS-1 Using the One-Factor-at-a-Time Approach [PDF]

Vasanthabharathi Venkatraman, Lakshminarayanan Ramasamy, Jaya lakshmi Singaram   +2 more
openalex   +1 more source

Host‐driven hepatic conversion of gut microbiota‐derived putrescine to spermidine mediates mannose's protective effects against hepatic steatosis in zebrafish

iMeta, EarlyView.
Evidence for liver metabolism of gut‐derived microbial compounds into beneficial secondary metabolites has been lacking. Here, we demonstrate that Cetobacterium somerae (C. somerae), enriched by mannose supplementation under high‐fat diet conditions, convert arginine into putrescine.
Delong Meng, Zhen Zhang, Tsegay Teame, Benjamin Earl Niemann, Rui Xia, Shichang Xu, Yajie Zhao, Yalin Yang, Chao Ran, Le Luo Guan, Zhigang Zhou   +10 more
wiley   +1 more source

Response of characteristic hormones in tea roots and leaves under magnesium regulation and their balancing regulation on growth and quality. [PDF]

Front Plant Sci
Jia X, Wang Y, Wang T, Zhu B, Weng Q, Liao Y, Gu J, Luo Y, Zhang Q, Ye J, Wang H.   +10 more
europepmc   +1 more source

A stable near IR switchable electrochromic polymer based on an indole-substituted nickel dithiolene

, 2009
Simon Dalgleish, Neil Robertson
openalex   +2 more sources

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source