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Mushroom-Derived Indole Alkaloids
Journal of Natural Products, 2017Mushrooms are known to produce over 140 natural products bearing an indole heterocycle. In this review, the isolation of these mushroom-derived indole alkaloids is discussed, along with their associated biological activities.
Joshua A. Homer, Jonathan Sperry
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Moschamine-Related Indole Alkaloids
2018Moschamine-related alkaloids originate mainly from feruloylserotonin by cyclization or dimerization. This review provides a comprehensive overview on the achievements in the field of moschamine-related alkaloids. In the isolation part, a detailed structural characterization of moschamine-related alkaloids is followed by their spectral data. Besides the
Chengfeng, Xia, Xiaogang, Tong
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Bioorganic Chemistry, 1977
Abstract Because of the nonspecific incorporation of acetate into the monoterpenoid portion of the indole alkaloids, the amino acid leucine has been investigated as an alternative precursor. Incorporations of leucine into the alkaloids vindoline and catharanthine in Vinca rosea are found to be 0.07 and 0.02%, respectively, levels comparable with ...
Donald C. Wigfield, Betty P. Wen
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Abstract Because of the nonspecific incorporation of acetate into the monoterpenoid portion of the indole alkaloids, the amino acid leucine has been investigated as an alternative precursor. Incorporations of leucine into the alkaloids vindoline and catharanthine in Vinca rosea are found to be 0.07 and 0.02%, respectively, levels comparable with ...
Donald C. Wigfield, Betty P. Wen
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Cytotoxicity of Modified Indole Alkaloids
Journal of Pharmaceutical Sciences, 1979Indole alkaloids of the iboga series were structurally modified by incorporation of a 3,4-dimethoxybenzyl or -benzoyl unit so that they contained the N-O-O triangle required for antileukemic activity according to the triangulation hypothesis. The cytotoxicities of the modified alkaloids in the in vitro P-388 system were not significantly increased over
D G, Kingston, S M, Sami
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Indole alkaloids from Gelsemium elegans
Phytochemistry, 2019Five previously undescribed monoterpenoid indole alkaloids were isolated from the roots of Gelsemium elegans. Their structures with absolute configurations were elucidated by HRESIMS, X-ray diffraction, ECD spectra, and molecular modeling. 19,20-Epoxyhumantenine is a humantenine-type alkaloid with an epoxypropyl group at the C-20 position, (4R)-19-oxo ...
Ming-Xue, Sun +7 more
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Indole alkaloids from Ervatamia chinensis
Phytochemistry, 2012Four vobasinyl-ibogan type bisindole alkaloids, ervachinines A-D (1-4), along with 12 known terpenoid indole alkaloids, were isolated from the whole plant of Ervatamia chinensis. Their structures were elucidated by analysis of spectroscopic data, including 1D and 2D NMR, and the absolute configurations of 1-4 were determined by CD exciton chirality ...
Ling-Li, Guo +9 more
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Indole Prenylation in Alkaloid Synthesis
2011Important biologically active indole alkaloids are decorated with prenyl (3,3-dimethylallyl) and tert-prenyl (1,1-dimethylallyl) groups. Covering the literature until the end of 2010, this review article comprehensively summarises and discusses the currently available technologies of prenylation and tert-prenylation of indoles, which have been applied ...
Thomas, Lindel +2 more
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1991
Publisher Summary This chapter focuses on new indole-containing natural products and their biological activity. A tremendous increase in the number of indole natural products has occurred in the areas of plant alkaloids, fungal metabolites, and marine natural products.
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Publisher Summary This chapter focuses on new indole-containing natural products and their biological activity. A tremendous increase in the number of indole natural products has occurred in the areas of plant alkaloids, fungal metabolites, and marine natural products.
openaire +1 more source