Results 141 to 150 of about 1,668,623 (259)

Contilisant-Belinostat Hybrids: Polyfunctionalized Indole Derivatives as Multineurotarget Drugs for the Potential Treatment of Alzheimer's Disease. [PDF]

ACS Pharmacol Transl Sci
Schäker-Hübner L, Toledano-Pinedo M, Eimermacher S, Krasniqi V, Porro-Pérez A, Tan K, Horn G, Stegen P, Elsinghorst PW, Wille T, Pietsch M, Gütschow M, Marco-Contelles J, Hansen FK.   +13 more
europepmc   +1 more source

Developing 3-(2-Isocyano-6-methylbenzyl)-1H-indole Derivatives to Enhance the Susceptibility of Serratia marcescens by Occluding Quorum Sensing. [PDF]

ACS Infect Dis, 2023
Wang J, Yang JY, Durairaj P, Wang W, Tang S, Wang D, Cai CY, Jia AQ.   +7 more
europepmc   +1 more source

Probing the Influence of Sulfur–Aromatic Interactions on the Electronic Structure of Gas‐Phase Peptides

Chemistry – A European Journal, EarlyView.
Just as fingerprints reveal identity, spectroscopic fingerprints reveal molecular secrets. In this article, we show parts of the unique fingerprint of the sulfur–aromatic interaction. By measuring how this force alters the electronic structure of gas‐phase peptides, we provide a fundamental understanding of interactions that give insights into the ...
Laura Pille, Carlos Ortiz‐Mahecha, Bart Oostenrijk, Juliette Leroux, Marion Girod, Konstantin Hirsch, Luke MacAleese, Robert Horst Meißner, Debora Scuderi, Isaak Unger, Vicente Zamudio‐Bayer, Sadia Bari, Lucas Schwob   +12 more
wiley   +1 more source

Indole derivatives display antimicrobial and antibiofilm effects against extensively drug-resistant <i>Acinetobacter baumannii</i>. [PDF]

Microbiol Spectr
Li J, Xie L, Lin F, Ling B.
europepmc   +1 more source

Click Capture SELEX for the Identification of Click‐Modified Aptamers Targeting Small Molecules in Solution

Chemistry – A European Journal, EarlyView.
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke, Carmelo Di Primo, Felix Bernhardt, Alea Schröder, Christian Renzl, Günter Mayer   +5 more
wiley   +1 more source

Bio-informed synthesis of marine-sourced indole derivatives: suppressing gram-negative bacteria biofilm and virulence. [PDF]

BMC Biol
Golberg K, Elouarzaki K, Kagan BE, Shagan M, Shemesh N, Kramarsky-Winter E, Ben-Zvi A, Nebenzahl YM, Marks RS, Kushmaro A.   +9 more
europepmc   +1 more source

Evaluation of the anti-inflammatory, analgesic, anti-pyretic and anti-ulcerogenic potentials of synthetic indole derivatives. [PDF]

Sci Rep, 2023
Siddique S, Ahmad KR, Nawaz SK, Raza AR, Ahmad SN, Ali R, Inayat I, Suleman S, Kanwal MA, Usman M.   +9 more
europepmc   +1 more source

Photoinduced Hydrogenative Dearomatization With Homocoupling of Quinolines to Construct Octahydro‐4,4'‐biquinolines

Chemistry – A European Journal, EarlyView.
Dearomative homocoupling of quinolines into 1,1',2,2',3,3',4,4'‐octahydro‐4,4'‐biquinoline (OHBQ) is reported. The photoexcited boron complex, in situ generated from quinoline, HB(pin), and KOtBu, enables the unprecedented homocoupling of tetrahydroquinolines that is challenging in the ground state, expanding the chemical diversity of OHBQ derivatives.
Mone Suzuki, Asuha Shimose, Yuki Nagashima   +2 more
wiley   +1 more source

Synthesis of Indole Derivatives via Aryl Triazole Ring-Opening and Subsequent Cyclization. [PDF]

Molecules
Burcevs A, Sebris A, Novosjolova I, Mishnev A, Turks M.   +4 more
europepmc   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source