Results 51 to 60 of about 6,883 (206)

Radical‐Polar Crossover Bicyclization Enables a Modular Synthesis of Saturated Bicyclic Amines

Advanced Science, Volume 12, Issue 25, July 3, 2025.
Herein, we report the successful realization of a radical‐polar crossover bicyclization reaction from easily available cyclopropylamines and substituted alkenes through photoredox catalysis. This approach introduces an innovative methodology for the de novo synthesis of a diverse collection of 4/5‐, 5/5‐, 6/5‐,7/5‐ and 5/6‐fused saturated bicyclic ...
Dewei Feng, Xiao Geng, Lingling Zuo, Zhifang Li, Lei Wang   +4 more
wiley   +1 more source

The MdHB7L–MdICE1L–MdHOS1 Module Fine‐Tunes Apple Cold Response via CBF‐Dependent and CBF‐Independent Pathways

Advanced Science, Volume 12, Issue 25, July 3, 2025.
In early cold response, MdICE1L utilizes MdHB7L as a cofactor to facilitate the transcriptional activation of MdCBFs, thereby activating cold signaling rapidly and strongly. Subsequently, MdICE1L is degraded by MdHOS1. Meanwhile, MdHB7L is released and accumulates.
Jie Yang, Na Li, Ming Li, Ran Yi, Lina Qiu, Kangning Wang, Shuang Zhao, Fengwang Ma, Ke Mao   +8 more
wiley   +1 more source

Transcriptomics and metabolomics analyses provide insights into postharvest ripening and senescence of tomato fruit under low temperature

Horticultural Plant Journal, 2023
Tomato is one of the most important vegetable crops in the world and is a model plant used to study the ripening of climacteric fleshy fruit. During the ripening process of tomato fruit, flavor and aroma metabolites, color, texture and plant hormones ...
Chunmei Bai, Caie Wu, Lili Ma, Anzhen Fu, Yanyan Zheng, Jiawei Han, Changbao Li, Shuzhi Yuan, Shufang Zheng, Lipu Gao, Xinhua Zhang, Qing Wang, Demei Meng, Jinhua Zuo   +13 more
doaj  

Transcriptomic and phosphoproteomic profiling and metabolite analyses reveal the mechanism of NaHCO3-induced organic acid secretion in grapevine roots

BMC Plant Biology, 2019
Background Organic acid secretion is a widespread physiological response of plants to alkalinity. However, the characteristics and underlying mechanism of the alkali-induced secretion of organic acids are poorly understood.
Guangqing Xiang, Wanyun Ma, Shiwei Gao, Zhongxin Jin, Qianyu Yue, Yuxin Yao   +5 more
doaj   +1 more source

4‐HIAA Blocks Methamphetamine‐Induced Conditioned Place Preference in Mice Through Modulation of the 5‐HT Pathway in the Nucleus Accumbens

Addiction Biology, Volume 30, Issue 7, July 2025.
4‐HIAA crosses the blood–brain barrier. Treatment (1‐mg/kg) inhibited CPP acquisition, promoted extinction and prevented relapse. These behavioural effects were associated with changes in nucleus accumbens 5‐HT expression. ABSTRACT 4‐hydroxyindole‐3‐acetic acid (4‐HIAA) is a metabolite of psilocin.
Yanan Wu, Ju Ran, Jinqiu Mo, Jing Wang
wiley   +1 more source

Destruction of indoleacetic acid [PDF]

Archives of Biochemistry and Biophysics, 1962
Abstract Kinetics of enzymic oxidation of indoleacetic acid (IAA) are interpreted as indicating that the reaction has an autocatalytic, cyclical mechanism involving unstable intermediates whose formation and disappearance are important in determining the over-all reaction rate.
openaire   +4 more sources

The Mechanism Exploration of Traditional Chinese Medicine's “Different Treatments for Same Disease” Concept in Osteoporosis Therapy: A Serum Metabolomics Study

Journal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT The “different treatments for same disease” is an important concept of traditional Chinese medicine (TCM) therapy. In TCM, osteoporosis (OP) treatment is aimed at invigorating blood, strengthening spleen, and tonifying kidneys, and their typical herbs are Angelica sinensis (Oliv.) Diels (Danggui, DG), Poria cocos (Schw.) Wolf (Fuling, FL), and
Jingyuan Wen, Xuefeng Li, Zhen Wu, Liu Jiangyuan, Guanyin Wang, Xu Wang, Zhengsheng Bao, Yang Yu, Pinger Wang, Zhenyu Shi, Bing Xu, Yunhuo Cai, Hongting Jin, Jiali Chen   +13 more
wiley   +1 more source

Bacillus coagulans regulates gut microbiota and ameliorates the alcoholic-associated liver disease in mice

Frontiers in Microbiology
IntroductionAlcoholic-associated liver diseases (ALD) are now widespread issues worldwide. Alcoholic-induced chronic dysbiosis of the gut microbiota is one of the factors in the pathophysiology of ALD.MethodsIn this work, we employed a chronic-binge ...
Zhenzhen Liu, Tong Liu, Zhenting Zhang, Zhenting Zhang, Yurong Fan   +4 more
doaj   +1 more source

Advancements in Water‐Saving Strategies and Crop Adaptation to Drought: A Comprehensive Review

Physiologia Plantarum, Volume 177, Issue 4, July/August 2025.
ABSTRACT Drought stress, which is one of the most critical environmental constraints affecting global crop productivity, is exacerbated by climate change and increased atmospheric water demand. This review comprehensively examines plant responses to drought, integrating physiological, morphological, biochemical, and genetic adaptations that contribute ...
Juan D. Franco‐Navarro, Yaiza Gara Padilla, Sara Álvarez, Ángeles Calatayud, José Manuel Colmenero‐Flores, María José Gómez‐Bellot, José Antonio Hernández, Isabel Martínez‐Alcalá, Consuelo Penella, Juan Gabriel Pérez‐Pérez, María Jesús Sánchez‐Blanco, María Tasa, José Ramón Acosta‐Motos   +12 more
wiley   +1 more source

Therapeutic Potential of Polyphenols in Targeting Th17/Treg Balance for Intestinal Barrier Maintenance

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
ABSTRACT The integrity of the intestinal barrier is essential for overall health. Disruption of tight junction (TJs) proteins negatively affects intestinal barrier function, leading to immune imbalances and causing a variety of pathological conditions that are closely associated with the pathogenesis of multiple diseases.
Jiaojiao Fu, Zhenghua Zhao, Da Zhou, Sijing Liu   +3 more
wiley   +1 more source