Results 101 to 110 of about 3,221 (136)

Neovascular pruning by IDO1 inhibitors can potentiate immunogenic cytotoxicity of ischemia-targeted agents to synergistically enhance anti-PD-1 responsiveness. [PDF]

J Immunother Cancer
Shen SC, Dey S, DuHadaway JB, Sutanto-Ward E, Hampton MT, Kozlov SV, Prendergast GC, Muller AJ.   +7 more
europepmc   +1 more source

IDO-Mediated Immune and Metabolic Dysregulation in Schwann Cells Exposed to <i>Mycobacterium leprae</i>. [PDF]

Cells
Rahman AU, Santana RC, de Pinho Pereira MM, Moura CLDS, da Silva DS, Araujo OC, Leal-Calvo T, Espasandin I, da Silva TP, Sarno EN, de Andrade Silva BJ, Menna-Barreto RSF, Jardim MM, de Macedo CS, Lara FA, Pinheiro RO.   +15 more
europepmc   +1 more source

Agathisflavone Modulates the Kynurenine Pathway and Glial Inflammatory Responses with Implications for Neuroprotection. [PDF]

Int J Mol Sci
Argolo DS, Oliveira LMG, Santos CCD, da Penha Gonçalves LV, Loiola EC, de Freitas Souza BS, Barreto GE, Butt AM, David JM, Branco A, Reis IMA, Azevedo-Silva A, Costa SL, Costa MFD.   +13 more
europepmc   +1 more source

Phosphorylation of ITIM motifs drives the structural transition of indoleamine 2,3-dioxygenase 1 between enzymatic and non-enzymatic states. [PDF]

Protein Sci
Hoffka G, Hornyák L, Székvölgyi L, Miskei M.   +3 more
europepmc   +1 more source

Reprogramming of the kynurenine pathway impairs NAD⁺ homeostasis and mediates doxorubicin-induced cardiotoxicity in mice. [PDF]

Redox Biol
Li D, Zhang Y, Kuang Y, Lin Z, Wang P, Jiang J, Pi W, Ma Q.   +7 more
europepmc   +1 more source

Dietary tryptophan augments cancer-associated venous thrombogenicity mitigated by indoleamine 2,3-dioxygenase 1 inhibition. [PDF]

Blood Adv
Lotfollahzadeh S, Jose A, Yang X, Bathla T, Lazowski A, Hoekstra I, Sethuraman K, Potluri S, Dulberger KN, La J, Fillmore NR, Piqueras MDC, Lee N, Cabral H, Ravid K, Chitalia VC.   +15 more
europepmc   +1 more source

Investigation of the Impact of Tryptophan-Metabolizing Enzymes and Kynurenic Acid on Antibody-Mediated Glomerulonephritis. [PDF]

FASEB J
Umeda R, Ito Y, Minatoguchi S, Koide S, Takahashi K, Hayashi H, Hasegawa M, Yuzawa Y, Yamamoto Y, Saito K, Tsuboi N.   +10 more
europepmc   +1 more source

Effect of Exogenous of Transforming Growth Factor-β1 on Pregnancy Outcome in Mice with Recurrent Pregnancy Loss by Persistent Enhancement of Placental Tissue Indoleamine 2,3-Dioxygenase Expression. [PDF]

Int J Fertil Steril
Wen X, Chen X, Li M, Zhou J, Dao S, Li S, Cheng H, Zhao S, Huang G.   +8 more
europepmc   +1 more source

Gut microbiota L-ornithine promotes resistance to obesity through metabolites mediated immunosuppressive macrophages. [PDF]

Cell Mol Life Sci
Li Y, Liu Y, Wang J, Gao Y, Zhang Y, Yang R.   +5 more
europepmc   +1 more source

Design, Synthesis, and Structural Evolution of Pseudo-Natural Product IDO1 Inhibitors and Degraders. [PDF]

Angew Chem Int Ed Engl
Cheng XF, Lucas B, Lampe P, Ugel S, Chen S, Unger A, Bischoff M, Adariani SR, Naredla KR, Kumar K, Schmidt A, Strohmann C, Janning P, Gasper R, Lucas M, Gersch M, Sievers S, Bronte V, Ziegler S, Waldmann H.   +19 more
europepmc   +1 more source