Results 11 to 20 of about 172,741 (147)

Indoleamine 2,3-Dioxygenase Regulates Placental Trophoblast Cell Invasion [PDF]

Int J Mol Sci
To clarify the physiological importance of the tryptophan catabolizing enzyme, indoleamine 2,3-dioxygenase, in human pregnancy, we have studied how the expression of this enzyme controls extravillous cytotrophoblast invasion into the decidua.
Yoshiki Kudo, Jun Sugimoto
core   +2 more sources

Indoleamine 2,3- Dioxygenase: A Novel Immunotherapeutic Target for Osteosarcoma [PDF]

, 2022
Introduction: Tumour-emitted molecules induce immunosuppression in the tumour microenvironment. An immunosuppressive enzyme, indoleamine 2,3-dioxygenase (IDO/IDO1), facilitates immune escape in several malignant tumours, including osteosarcoma ...
Farooq, Asim, Zulfiqar, Bilal, Asghar, Kashif   +2 more
core   +1 more source

Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: Expression, design optimization, uptake mechanism and nuclear localization [PDF]

, 2009
Copyright © The Author 2009. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses?by-nc/2.0/uk/) which permits ...
Seow, WY, George, AJT, Yang, Y-Y
core   +1 more source

sj-docx-1-try-10.1177_11786469221138456 – Supplemental material for Identification and Characterization of a Novel Dual Inhibitor of Indoleamine 2,3-dioxygenase 1 and Tryptophan 2,3-dioxygenase

, 2022
Supplemental material, sj-docx-1-try-10.1177_11786469221138456 for Identification and Characterization of a Novel Dual Inhibitor of Indoleamine 2,3-dioxygenase 1 and Tryptophan 2,3-dioxygenase by Saeko Yoshioka, Tomonori Ikeda, Sogo Fukuchi, Yurika Kawai,
Osamu Takikawa (230148), Daisuke Muraoka (611837), Katsumi Ohta (14198608), Akira Asai (446940), Naohisa Ogo (446936), Saeko Yoshioka (14198596), Sogo Fukuchi (14198602), Tomonori Ikeda (14198599), Yurika Kawai (14198605), Hisashi Murakami (565962)   +9 more
core   +1 more source

Mediating the death of dormant tumor cells

Molecular & Cellular Oncology, 2018
How immunological cues trigger cancer cell-intrinsic signaling pathways for their entering dormancy remains an enigma. In out recent studies, we found that IFN-β induces tumor-repopulating cells (TRC) into dormancy by activating Indoleamine-pyrrole 2,3 ...
Yuying Liu, Jiadi Lv, Bo Huang
doaj   +1 more source

IDO1 (indoleamine 2,3-dioxygenase 1) [PDF]

, 2010
Review on IDO1 (indoleamine 2,3-dioxygenase 1), with data on DNA, on the protein encoded, and where the gene is ...
Muller, AJ, MY Chang, Chang, MY, GC Prendergast, AJ Muller, Prendergast, GC   +5 more
core   +1 more source

Recombinant human indoleamine 2,3-dioxygenase

, 2021
Indoleamine 2,3-dioxygenase (IDO) is a heme-containing dioxygenase that catalyses the first and rate-limiting step in the kynurenine (Kyn) pathway of L-tryptophan (L-Trp)catabolism.
Priambudi Kosim-Satyaputra (12307877)
core   +1 more source

N‑Benzyl/Aryl Substituted Tryptanthrin as Dual Inhibitors of Indoleamine 2,3-Dioxygenase and Tryptophan 2,3-Dioxygenase

, 2019
Indoleamine 2,3-dioxygenase 1 (IDO1), which catalyzes the initial and rate-limiting step of the kynurenine pathway of tryptophan catabolism, has emerged as a key target in cancer immunotherapy because of its role in enabling cancers to evade the immune ...
Shengnan Zhang (1340988), Xishuai Li (1884145), Nan Hu (4067), Shuangshuang Yang (1884151), Qing Yang (67856), Xin Fang (134979), Dan Yang (65758), Leilei Guo (6734231), Zhanling Guo (7460843), Jin Chao He (7460846), Chunxiang Kuang (1783678)   +10 more
core   +2 more sources

IDO2 (indoleamine 2,3-dioxygenase 2) [PDF]

, 2010
Review on IDO2 (indoleamine 2,3-dioxygenase 2), with data on DNA, on the protein encoded, and where the gene is ...
Muller, AJ, MY Chang, Chang, MY, GC Prendergast, Metz, R, R Metz, AJ Muller, Prendergast, GC   +7 more
core   +1 more source

Vascular endothelial growth factor-A enhances indoleamine 2,3-dioxygenase expression by dendritic cells and subsequently impacts lymphocyte proliferation

Memorias do Instituto Oswaldo Cruz, 2014
Dendritic cells (DCs) are antigen (Ag)-presenting cells that activate and stimulate effective immune responses by T cells, but can also act as negative regulators of these responses and thus play important roles in immune regulation.
Luciana Cavalheiro Marti, Lorena Pavon, Patricia Severino, Tatiana Sibov, Daiane Guilhen, Carlos Alberto Moreira-Filho   +5 more
doaj   +1 more source