Results 61 to 70 of about 3,209 (136)
Melatonin inhibira lipidnu peroksidaciju u jetri štakora uzrokovanu benzenom [PDF]
We studied the antioxidative role of melatonin against benzene toxicity in rat liver. The inhibition of mitochondrial and microsomal lipid peroxidation differed between 24-hour (single-dose), 15-day, and 30-day treatments.
A-R Meki +48 more
core +2 more sources
Role of Kynurenine Pathway in Glioblastoma [PDF]
In brain, the tryptophan degradation products through the kynurenine pathway exhibit neuromodulatory and inflammatory effects and have been related to the progression of neurodegenerative disorders, furthermore, their protagonism on the modulation of ...
Arellano, Nora Karen Olascoaga +7 more
core +1 more source
The expression of programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) indicate the efficacy of anti-PD-1/PD-L1 therapy in colorectal cancer (CRC), but are less useful for monitoring the efficacy of therapy of CRC liver metastasis (CRLM). This
Kashihara, Hideya +8 more
core
Modulation of Tumor Tolerance in Primary Central Nervous System Malignancies [PDF]
Central nervous system tumors take advantage of the unique immunology of the CNS and develop exquisitely complex stromal networks that promote growth despite the presence of antigen-presenting cells and tumor-infiltrating lymphocytes.
Johnson, Theodore S. +2 more
core +3 more sources
An indicator of cancer: downregulation of Monoamine Oxidase-A in multiple organs and species [PDF]
Background Identifying consistent changes in cellular function that occur in multiple types of cancer could revolutionize the way cancer is treated. Previous work has produced promising results such as the identification of p53.
Bashaw, Meredith J +3 more
core +3 more sources
Spectroscopic and Thermodynamic Characterization of Human 3-Hydroxyanthranilate-3,4-Dioxygenase [PDF]
3-Hydroxyanthranilate-3,4-dioxygenase (HAO) is a non-heme iron dependent enzyme that catalyzes the oxidative ring opening of 3-hydroxyanthranilate (HAA) which is an intermediate in the kynurenine pathway and its ring opening is the final enzymatic step ...
Henry, Calmour
core +1 more source
Discovery of Highly Potent Benzimidazole Derivatives as Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors: From Structure-Based Virtual Screening to in Vivo Pharmacodynamic Activity [PDF]
Serafini, M.
core +1 more source
Indoleamine-pyrrole 2,3-dioxygenase (INDO; IDO) [PDF]
openaire +1 more source

