Results 101 to 110 of about 27,606 (220)

Harnessing Toluene Solvent as a Reactant: Regioselective Benzyl Radical Addition to Multi‐π 1,5‐Enynes in a Copper‐Catalyzed Cascade to Indenes

Chemistry – A European Journal, EarlyView.
A copper‐catalyzed three‐component radical cascade of 1,5‐enynes with toluene and benzoic acids enables regioselective benzyl radical addition to multi‐Π systems, efficiently delivering polysubstituted indenes from an abundant solvent feedstock. ABSTRACT C─H activation of toluene generates a benzyl radical that undergoes C─C coupling, converting an ...
Saideh Rajai‐Daryasarei, Fatemeh Chahardehi, Mohammad Mahdi Sharifani, Morteza Jamshidi, Robert Stranger, Frank Rominger, Alireza Ariafard, Saeed Balalaie   +7 more
wiley   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, EarlyView.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Visible-Light-Induced Radical Cascade [4 + 2]/[4 + 2] Cycloaddition of Underexplored <i>N</i>-Acryloyl Indoles To Access Dihydropyrido[1,2-<i>a</i>]-indolones. [PDF]

Org Lett
Bishir C, Milton S, Hubbard A, Indalsingh M, Abufouz Z, Mei L.   +5 more
europepmc   +1 more source

Dual Ligand‐Enabled Nondirected C─H Olefination of (Hetero)Arenes for the Synthesis of Clickable Derivatives

Chemistry – A European Journal, EarlyView.
We report an efficient method for late‐stage installation of “clickable” alkyne groups into diverse (hetero)arenes. Using a dual‐ligand palladium catalyst that combines an NASA ligand with an N‐heterocycle, an acrylate unit bearing a terminal alkyne can be introduced via nondirected C─H activation.
Tommaso Braga, Maria Hergert, Manuel van Gemmeren   +2 more
wiley   +1 more source

Direct Fluoroformylation of the C3-Position of Indoles with 2,4-Dinitro(trifluoromethoxy)benzene as Fluorocarbonyl Source. [PDF]

ChemistryOpen
Wisson L, Hanquet G, Toulgoat F, Billard T, Leroux FR, Panossian A.   +5 more
europepmc   +1 more source

Enantioselectivity in Transition Metal Catalyzed Propargylic Substitution Reactions: A Theoretical Perspective

Chemistry – A European Journal, EarlyView.
Recent theoretical efforts to elucidate the origin of enantioselectivity in transition metal‐catalyzed propargylic substitution reactions are highlighted in this review. ABSTRACT In recent years, asymmetric catalytic propargylic substitution reactions have undergone remarkable development, enabling the construction of chiral carbon centers adjacent to ...
Ken Sakata, Yoshiaki Nishibayashi
wiley   +1 more source

Functional Training Mitigates Reduced Circulating Indole-3-Lactate Levels in Persons With Relapsing-Remitting Multiple Sclerosis. [PDF]

Acta Physiol (Oxf)
Wences Chirino T, Adammek F, Belen S, Winker M, Proschinger S, Rademacher A, Schlagheck ML, Schenk A, Kupjetz M, Walzik D, Warnke C, Reuter M, Rosenberger F, Meyer T, McCann A, Ueland PM, Joisten N, Zimmer P.   +17 more
europepmc   +1 more source

Generation of a Ground‐State Electron Donor Utilizing Stored Light Energy

Chemistry – A European Journal, EarlyView.
Chemically stored light energy enables the generation of dianion reductants (∼−2.7 V) from vicinal diols derived from diaryl ketone photodimerization. These ground‐state electron donors efficiently reduce challenging substrates at room temperature, including aryl bromides, alkyl iodides, and sulfonamides.
Marc Taillefer, Éric Clot, Alexis Prieto   +2 more
wiley   +1 more source

Recent developments in the organocatalytic asymmetric cycloaddition/annulation reactions involving indolylmethanols. [PDF]

RSC Adv
Patel A, Harshit, Iype E, Kumar I.
europepmc   +1 more source

Insights into the Photocatalytic Arene Bromination Enabled by Cs2AgBiBr6 Microparticles

Chemistry – A European Journal, EarlyView.
A sustainable photocatalytic bromination of electron‐rich arenes is enabled by low‐toxicity Cs2AgBiBr6 double‐perovskite microparticles using HBr as an atom‐economical bromine source. Surface‐derived bromine radicals drive highly selective mono‐bromination under mild conditions.
Daniele Conelli, Chiara Lo Porto, Mokurala Krishnaiah, Kimmo Lahtonen, G. Krishnamurthy Grandhi, Nicola Margiotta, Paola Vivo, Gian Paolo Suranna, Roberto Grisorio   +8 more
wiley   +1 more source