Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen +9 more
wiley +1 more source
Gut microbiota derived indoles are altered and associate with immune activation in moderate and severe carotid stenosis. [PDF]
Stø K +9 more
europepmc +1 more source
A review of the inhibitory waste metabolites produced during mAb biomanufacturing
The review highlights inhibitory metabolites in CHO cell cultures, such as lactate, ammonia, isobutyrate, and isovalerate, impacting growth and productivity. Identification methods include LC/MS‐based metabolomics, while control strategies involve media optimization, genetic engineering, and process adjustments (pH, temperature).
Zhao Wang +5 more
wiley +1 more source
Dual screen for gut metabolites suppressing enterobacterial growth and invasiveness reveals structure-activity relationships among anti-infective indoles. [PDF]
Bergholtz A +9 more
europepmc +1 more source
The structural design strategy employing the Y6‐BO interfacial lamination suppresses dark current by limiting solvent‐induced interfacial damage through the formation of uniformly arranged interfaces while optimizing charge transport to achieve superior detectivity.
Jihyun Lim +4 more
wiley +1 more source
Hydrogen‐release processes in silicon chemistry occur across a broad spectrum of systems, including crystalline silicon surfaces, nanoporous materials, Zintl phases, and molecular hydrides. This Review highlights how Si─H activation and H2 evolution are governed by structure, coordination environment, and dynamic access to reactive geometries, with ...
Robin Rothfelder, Jonathan O. Bauer
wiley +1 more source
Recent progress in catalytic asymmetric synthesis of triarylmethanes. [PDF]
Han Y, Li L, Loh TP.
europepmc +1 more source
Photostability of Cyanine Dyes and Its Correlation to Their Photothermal and Photodynamic Effects
Photostability (PS) of dyes is a crucial parameter for performance in biological applications, yet often underrated. Here PS of several cyanines is investigated. The method is carefully evaluated and designed as a general and easy tool to compare PS of NIR dyes.
Clara Schäfer, Bo W. Laursen
wiley +1 more source
Benzoic acid versus salicylic acid efficacy in regulating growth, accumulation of secondary metabolites and NO<sub>3</sub> content of Swiss chard (Beta vulgaris L. var. cicla). [PDF]
AbdelMotlb NA +7 more
europepmc +1 more source
C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens +3 more
wiley +1 more source

