Results 201 to 210 of about 44,366 (284)

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

Noise‐Blocking Interfacial Lamination of Small‐Molecule Acceptors for Enhanced Signal Clarity in Organic Photodetectors

open access: yesCarbon Energy, EarlyView.
The structural design strategy employing the Y6‐BO interfacial lamination suppresses dark current by limiting solvent‐induced interfacial damage through the formation of uniformly arranged interfaces while optimizing charge transport to achieve superior detectivity.
Jihyun Lim   +4 more
wiley   +1 more source

Routes to Cyclobutadiene and Cycloallyl Pt(II) Complexes: Dicationic Bis(Alkyne) Species as Intermediates

open access: yesChemistry – A European Journal, EarlyView.
This work demonstrates the synthesis of cationic Pt(II) η3‐cycloallyl complexes, and experimental and computational studies show a ligand bite‐angle dependence of their formation rates. The reactivity of these complexes with Brønsted acids was investigated, leading to the formation of cationic and dicationic Pt(II) η4‐cyclobutadiene complexes ...
Ouchan He   +6 more
wiley   +1 more source

One‐Shot Pd(II)‐Catalyzed Multiple C–H Activation Enables Modular Construction of Fluorenylidene Oxindole‐Based Multi(Polycyclic) Aromatic Enes

open access: yesChemistry – A European Journal, EarlyView.
A one‐shot Pd(II)‐catalyzed C─H activation strategy enables the rapid conversion of simple linear propiolamides into structurally diverse mono‐, di‐, and tri‐olefin‐bridged MPAEs. This cascade process orchestrates up to six sequential C–H activations in a single operation, providing streamlined access to highly conjugated architectures.
Haiyu Wang   +4 more
wiley   +1 more source

Commensal yeast Malassezia produces tryptophan metabolites to promote tissue homeostasis via the aryl hydrocarbon receptor in mice. [PDF]

open access: yesNat Microbiol
Gushiken-Ibañez E   +8 more
europepmc   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

open access: yesChemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal   +3 more
wiley   +1 more source

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