Results 231 to 240 of about 200,870 (399)

Photokatalytische Hydrierung von Chinolinen zu 1,2,3,4‐Tetrahdyrochinolinen mit Wasser als Wasserstoffatomdonor

open access: yesAngewandte Chemie, EarlyView.
Für die trans‐selektive Hydrierung von Chinolinen unter Verwendung von Wasser als Wasserstoffatomquelle wird ein sequentieller Prozess vorgestellt, der eine Hydrierung und eine anschließende Stereomutation kombiniert. Mechanistische Studien zeigen, dass die Hydrierung durch einen Kaskadenprozess abläuft, der eine initiale cis‐selektive ...
Jingjing Zhang   +6 more
wiley   +1 more source

SAR exploration of the non‐imidazole histamine H3 receptor ligand ZEL‐H16 reveals potent inverse agonism

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
ZEL‐H16 (1) has been disclosed to be a high‐affinity non‐imidazole H3R (partial) agonist. However, it was found that 1 acts as an inverse agonist for Gαi in various assays. Concise structure–activity relationship studies, molecular pharmacology, and docking were used to shed more light on the properties of 1.
Gábor Wágner   +12 more
wiley   +1 more source

Reverse Regioselective Dicarbofunctionalization via Anti‐Michael‐Type Addition

open access: yesAngewandte Chemie, EarlyView.
A reverse regioselective dicarbofunctionalization of acrylamides via anti‐Michael‐type addition is reported. Various (hetero)arene nucleophiles and carbon electrophiles were incorporated in a manner opposite to conventional regioselectivity. A key feature of this reaction is the formation of an alkylpalladium intermediate, which enables the achievement
Hirotsugu Suzuki   +2 more
wiley   +2 more sources

Recent advances in catalytic approaches for the synthesis of 3-substituted indoles: mechanisms and strategies. [PDF]

open access: yesRSC Adv
Abdu Musad Saleh E   +9 more
europepmc   +1 more source

INDOL STUDIES [PDF]

open access: yesJournal of Bacteriology, 1925
openaire   +2 more sources

Access to N‐Monofluoromethylated (Thio)Carbamates, Formamides, Alkynamides, and Related Derivatives

open access: yesAngewandte Chemie, EarlyView.
The first general synthetic access to N‐CH₂F and N‐CHRF carbamates, thiocarbamates, formamides, alkynamides, and related compounds is disclosed. The method involves the direct synthesis of carbamoyl fluoride building blocks from readily available amines, followed by their derivatization. Abstract This work presents the first general synthetic access to
Filip G. Zivkovic   +3 more
wiley   +2 more sources

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