Results 231 to 240 of about 104,731 (310)

Selective Hydrogenation of Heteroarenes Using Supported Ruthenium Phosphide Nanoparticle Catalysts. [PDF]

J Am Chem Soc
Ghazi Zahedi H, Hertel J, Paul B, Kang L, Johny J, Wu Y, Wiegand T, DeBeer S, Leitner W, Bordet A.   +9 more
europepmc   +1 more source

Unified ChemicalSynthesis of Corynanthe-Sarpagine-AjmalineType Monoterpene Indole Alkaloids: A Biomimetic Approach

Ya-Kui Sun (22253432), Xiao-Feng Guo (1832314), Yu Bu (22253435), Jin-Bao Qiao (1796170), Yu-Ming Zhao (2102965)   +4 more
openalex   +1 more source

An Indole-Rich Postbiotic Reduces Itching in Dogs: A Randomized, Double-Blinded Placebo-Controlled Study [PDF]

Aylesse Sordillo, Jonna Heldrich, Robert Turcotte, Ravi U. Sheth   +3 more
openalex   +1 more source

A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

ChemMedChem, EarlyView.
A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova, Thomas M. Geiger, Lorenzo Cianni, Dominika E. Pieńkowska, Jan Gerhartz, Lina Read, Aleša Bricelj, Alexander Herrmann, Maurice Leon Nelles, Yuen Lam Dora Ng, Marcus D. Hartmann, Jan Krönke, Izidor Sosič, Radosław P. Nowak, Michael Gütschow, Christian Steinebach   +15 more
wiley   +1 more source

Synthesis, Anthelmintic Activity, and Mechanism of Action of 5-Aryl-1<i>H</i>-indoles. [PDF]

J Agric Food Chem
Kadlecová A, Dzedulionytė Müldür K, Peřina M, Bieleszová K, Zhang C, Kováříček D, Valderas-García E, Vítek D, Valikonytė M, Šačkus A, Solovjova J, Malinauskienė V, Doležal K, Novák O, Grundler FMW, Roy P, Martínez-Valladares M, Voller J, Schleker ASS, Žukauskaitė A.   +19 more
europepmc   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Three-Dimensional Quantitative Structure−Activity Relationship Study of the Cannabimimetic (Aminoalkyl)indoles Using Comparative Molecular Field Analysis

, 1998
Joong‐Youn Shim, Elizabeth R. Collantes, William J. Welsh, Babu Subramaniam, A­llyn C. Howlett, Michael A. Eissenstat, Susan J. Ward   +6 more
openalex   +1 more source

Metal‐Directed Self‐Assembly in a Beta‐Sheet Miniprotein Scaffold

European Journal of Inorganic Chemistry, EarlyView.
A rationally engineered miniprotein, V14C, which is based on the beta β‐sheet Foldon domain, self‐assembles via a metal‐binding site to form well‐defined oligomers in the presence of Zn2+, Hg2+, and Cd2+. This modular design expands the toolbox for creating custom metalloproteins, enabling studies of metal–protein interactions for biochemical functions
Chandan Muni Reddy, Marcos R. Conde González, Jürgen H. Gross, Franziska Thomas   +3 more
wiley   +1 more source

Recent advances in cyclization reactions of <i>ortho</i>-substituted <i>gem</i>-dibromoolefins. [PDF]

RSC Adv
Rajai-Daryasarei S, Naieni NR, Balalaie S.   +2 more
europepmc   +1 more source

Ultrasound assisted Mizoroki–Heck reaction catalyzed by Pd/C: Synthesis of 3-vinyl indoles as potential cytotoxic agents

, 2016
S. Bhavani, Mohd Ashraf Ashfaq, Rambabu Dandela, Mandava Venkata Basaveswara Rao, Manojit Pal   +4 more
openalex   +1 more source