Results 71 to 80 of about 104,731 (310)
Synthesis of α-functionalized α-indol-3-yl carbonyls through direct SN reactions of indol-3-yl α-acyloins [PDF]
, 2016 A new and efficient synthesis of α-functionalized α-indol-3-yl ketones from easily available indolyl α-acyloins is reported. This process, catalyzed by Brønsted or Lewis acids, involves an uncommon direct nucleophilic substitution reaction of a secondary
Martínez Lara, Fernando +2 more
core +1 more source
Advanced Science, EarlyView.An Automated ex vivo culture system BaSIC, tailored for SCN slices and cell culture, which automates medium exchange and ensures a stable internal environment is developed. BaSIC enables real‐time observation of tissue/cell responses to diverse but programmed stimuli.
Kui Han +7 more
wiley +1 more source
Silver and platinum-catalysed addition of O–H and N–H bonds to allenes [PDF]
, 2014 Transition-metal catalysed nucleophile addition to allenes is a very powerful tool for the synthesis of functionalised molecules containing heteroatoms, heterocycles in the intramolecular version, or allyl derivatives in the intermolecular version.
Munoz-Herranz, Maria
core +1 more source
Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits
Advanced Science, EarlyView.Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu +16 more
wiley +1 more source
Analysis of indole derivatives in methanolic extracts from mycelium of Agaricus bisporus cultured in vitro on liquid Oddoux medium [PDF]
, 2014 Methanolic extracts obtained from biomass of Agaricus bisporus (J.E. Lange) Imbach cultured in vitro were analyzed for qualitative and quantitative composition of non-hallucinogenic indole compounds in order to compare their amount with fruiting bodies ...
Hałaszczuk Patrycja +4 more
core +1 more source
Advanced Science, EarlyView.The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang +22 more
wiley +1 more source
The iso-Nazarov reaction [PDF]
, 2017 The construction of five-membered rings is essential in organic chemistry. In this context, pentannulation reactions that provide a straightforward access to cyclopentenones are of particular interest, as these structures are not only embedded in ...
Marsili, Lucía A. +2 more
core +1 more source
Advanced Science, EarlyView.Efficient and photostable organic solar cells (OSCs) are developed using giant small‐molecule donors (GSMDs) with controlled backbone planarity. By tuning alkyl side chain orientation, anti‐configured GSMD improved crystallinity and charge transport, yielding PCE of 15.4% and superior stability (t80% > 1500 h).
Hyerin Jeon +4 more
wiley +1 more source
Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids [PDF]
, 2019 A mosaic of cross-phyla chemical interactions occurs between all metazoans and their microbiomes. In humans, the gut harbors the heaviest microbial load, but many organs, particularly those with a mucosal surface, associate with highly adapted and ...
Mazmanian, Sarkis +2 more
core
Palladium-catalyzed acetylation of arenes. [PDF]
, 2014 A simple method for the preparation of aryl methyl ketones is reported. The transformation involves the Pd-catalyzed coupling of an acyl anion equivalent, acetyltrimethylsilane, with aryl bromides to afford the corresponding acetylated arenes in ...
Garg, Neil K, Ramgren, Stephen D
core +1 more source