Results 61 to 70 of about 887 (215)

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Estudio químico de los alcaloides presentes en las hojas de yerbamora (Solanum nigrum L.), originaria de los municipios de Pasto y Chachagüí. [PDF]

, 2017
Se evaluaron tres métodos de extracción de alcaloides en las hojas de variedades de yerbamora (Solanum nigrum L.) provenientes de los municipios de Obonuco y Chachagüí, encontrando que el método más adecuado de extracción fue la hidrólisis ácida en ...
Arturo P., Luis
core  

Estudio Conformacional de 1,2,3,4-tetrahidrocarbazol y triptolina mediante métodos computacionales y espectroscopía de rotación [PDF]

, 2022
En este TFG se han estudiado la triptolina y el tetrahidrocarbazol, dos derivados de indol precursores de fármacos en el área de la salud mental y la neurología. El trabajo ha incluido objetivos computacionales y experimentales.
Martin Cuesta, Sergio
core  

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

Advanced Science, EarlyView.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei, Wei Liu, Bili Cao, Dan Zhao, Chengqiang Wang, Xin Hou, Tangyuan Ning, Biao Gong   +7 more
wiley   +1 more source

Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p‐cresol Formation

Advanced Science, EarlyView.
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang, Yifeng Wei, Xumei Liu, Dazhi Liu, Zhenyu Liu, Yang Tong, Jinyu Yin, Ankanahalli N. Nanjaraj Urs, Meining Xing, Mark A. Harrison, Chuyuan Zhang, Sheng Yang, Yunzi Luo, Ee Lui Ang, Huimin Zhao, Yan Zhang   +15 more
wiley   +1 more source

Efecto del tiempo y tipo de cocción en la concentración de glucosinolatos de tres accesiones de mashua (Tropaelum tuberosum) [PDF]

, 2020
La mashua (Tropaeolum tuberosum), tubérculo andino cultivado por siglos en los andes del Perú, en cuya composición química en base seca del tubérculo alberga un importante contenido de proteínas, carbohidratos, vitamina C, compuestos fenólicos ...
Cairampoma Amaro, Jhonatan Benjamin
core  

Bayesian Optimisation for the Experimental Sciences: A Practical Guide to Data‐Efficient Optimisation of Laboratory Workflows

Advanced Intelligent Systems, EarlyView.
This study provides an introduction to Bayesian optimisation targeted for experimentalists. It explains core concepts, surrogate modelling, and acquisition strategies, and addresses common real‐world challenges such as noise, constraints, mixed variables, scalability, and automation.
Chuan He, Martin Singull, T. Jesper Jacobsson   +2 more
wiley   +1 more source

Rol hormonomodulador de los vegetales crucíferos en el cáncer de próstata [PDF]

, 2019
Introducción: El cáncer de próstata ha sido considerado la neoplasia de mayor incidencia en varones en la Argentina hasta el año 2018. Los alimentos y la nutrición son uno de los factores más relevantes en la tumorigénesis. Hay alimentos y principalmente
Rey Echalecu, Lara Sofía
core  

Enhancement of developmental defects in the boron‐deficient maize mutant tassel‐less1 by reduced auxin levels

Journal of Plant Nutrition and Soil Science, EarlyView., 2023
Abstract Background Plant responses to deficiencies of the micronutrient boron are diverse and go beyond the well‐characterized function of boron in cell wall crosslinking. To explain these phenotypic discrepancies, hypotheses about interactions of boron with various phytohormones have been proposed, particularly auxin.
Michaela S. Matthes, Norman B. Best, Janlo M. Robil, Paula McSteen   +3 more
wiley   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source