Results 91 to 100 of about 13,350 (226)
The crystal structures of the title compounds, C19H19NO and C31H34N2O, were determined as part of an experiment in an undergraduate teaching laboratory that demonstrates the relationship between molecular structure and function.
Joseph O. S. Beckett +5 more
doaj +1 more source
Tuning pKa in new molecules based on indolines for two-photon absorption bioimaging applications [PDF]
Fluorescence-based biosensors have become essential tools for modern biology, allowing real-time monitoring of biological processes within living cells.
Benitez-Martin, Carlos +2 more
core
Enantioselective Organocatalytic Cyclopropanations. The Identification of a New Class of Iminium Catalyst Based upon Directed Electrostatic Activation [PDF]
A new method for enantioselective organocatalytic cyclopropanation is described. This study outlines the identification of a new class of iminium catalyst based on the concept of directed electrostatic activation (DEA).
Kunz, Roxanne K., MacMillan, David W. C.
core +1 more source
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga +11 more
wiley +1 more source
The n-butyramido, isobutyramido, benzamido, and furancarboxamido functions profoundly modulate the electronics of the stilbene olefinic and NH groups and the corresponding radical cations in ways that influence the efficiency of the cyclization due ...
Noel Francis Thomas +7 more
doaj +1 more source
Facile Access to N‐Substituted Pyridyl Ligands
A modular, robust, and versatile Buchwald–Hartwig amination protocol that enables the rapid synthesis of bipyridine, phenanthroline, terpyridine, and pybox ligands bearing dialkylamine, diarylamine, and heteroaromatic N‐substituents. Pyridyl motifs equipped with N‐substituents can be powerful ligands for catalysis, yet their broader adoption is limited
Adam Petrik +5 more
wiley +1 more source
Chiral Aminophosphines as Catalysts for Enantioselective Double-Michael Indoline Syntheses
The bisphosphine-catalyzed double-Michael addition of dinucleophiles to electron-deficient acetylenes is an efficient process for the synthesis of many nitrogen-containing heterocycles.
Ohyun Kwon, San N. Khong
doaj +1 more source
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells [PDF]
Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS is a phenomenon that results from
Benitez-Martin, Carlos +4 more
core
Organic nanoparticulate photochromes [PDF]
Photochromic organic dyes can be widely used in materials for optically rewritable data storage, photonic switches, memories, sensors, or actuators. In recent years photochromic materials based on nanoparticles became particularly focused, since they can
Feczkó, Tivadar, Voncina, Bojana
core +1 more source
This review highlights the evolution of highly enantioselective oxazolidinone transformations enabled by C2‐symmetric ligands, with emphasis on chiral iron triad complexes as cost‐effective, environmentally benign alternatives to late‐transition‐metal catalysts.
Arthur David, Thierry Ollevier
wiley +1 more source

