Results 31 to 40 of about 43,564 (156)
Experimental Physiology, EarlyView.Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay +3 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Severe polyhydramnios occurs in 1%–2% of pregnancies and may be associated with maternal diabetes, fetal structural anomalies, genetic disorders, or remain idiopathic. Among the rare etiologies is Bartter syndrome, a renal tubular defect causing impaired salt reabsorption.
Fatemeh Shariati nia +5 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.ABSTRACT Objectives Effective management of post‐endodontic pain is crucial for patient comfort. Although ketorolac is used for this purpose, its efficacy relative to other analgesics remains uncertain. This study systematically assesses evidence from randomized clinical trials that investigate the comparative effectiveness of ketorolac and other ...
Ruijing Ping +4 more
wiley +1 more source
eFood, Volume 7, Issue 2, April 2026.Composition, biological activity and food application of banana biomass. ABSTRACT The global banana processing industry generates substantial organic waste in the form of peels, leaves, stems, and flowers, posing both environmental challenges and opportunities for valorization within a circular economy framework.
Bushra Iram Fatima +8 more
wiley +1 more source
Natural Sciences, Volume 6, Issue 2, April 2026.Dental pulp stem cellderived exosomes and folic acid are evaluated for their effects on gene expression in an in‐vitro periodontal injury model. Human gingival fibroblasts subjected to oxidative and mechanical injury are treated with folic acid, exosomes, or their combination.
Saghar Zarei +4 more
wiley +1 more source
Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 2, April 2026.ABSTRACT A rescue cervical cerclage is an emergency procedure aimed to prolong pregnancy and reduce the risk of preterm birth for women with an open cervix. This retrospective study assessed risk factors, perioperative management and outcomes for all attempted rescue cerclage over 3 years in a large tertiary hospital in Australia.
Madison Phung, Lisa Dawes
wiley +1 more source
Pravastatin Corrects Endothelial Dysfunction in Ex Vivo Uterine Radial Arteries in Preeclampsia
Acta Physiologica, Volume 242, Issue 4, April 2026.ABSTRACT Aim Endothelium‐dependent relaxation in isolated uterine radial arteries from normotensive (NT) and preeclamptic (PE) pregnancies, and the acute effects of pravastatin in the latter vessels were assessed. Pravastatin is hypothesized to alleviate endothelial dysfunction in PE via modulating aspects of NO and endothelium‐derived ...
Nathan M. Luque +11 more
wiley +1 more source
Advanced Science, Volume 13, Issue 16, 18 March 2026.This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang +12 more
wiley +1 more source