Results 101 to 110 of about 11,454 (213)
Plasma indoxyl sulfate and estimated glomerular filtration rate.
Indoxyl sulfate (IS), a uremic toxin, has cardiovascular as well as uremic toxicity. We evaluated the prognostic value of blood IS level for long-term outcome.This study followed 311 patients with coronary artery disease. Plasma IS level and estimated glomerular filtration rate (eGFR) were determined.
Daiji, Yoshikawa +8 more
openaire +2 more sources
Significant association between DII and depression in CKD patients aged ≤ 70 years. Linear association between DII and depression in CKD patients aged ≤ 70 years. Inflammation and residual renal function mediated the association between DII and depression.
Jialing Zhang, Qing Wang
wiley +1 more source
Binding Affinity and Capacity for the Uremic Toxin Indoxyl Sulfate
Protein binding prevents uremic toxins from removal by conventional extracorporeal therapies leading to accumulation in maintenance dialysis patients. Weakening of the protein binding may enhance the dialytic elimination of these toxins. In ultrafiltration and equilibrium dialysis experiments, different measures to modify the plasma binding affinity ...
Devine, Eric +4 more
openaire +4 more sources
Background Sarcopenia is the age‐related degeneration characterized with the decline of skeletal muscle mass, strength, and function. The imbalance of protein synthesis and degradation which jeopardizes immune, hormone regulation, and muscle‐motor neuron
Jia‐Rong Jheng +7 more
doaj +1 more source
Protein-Bound Uremic Toxins: New Insight from Clinical Studies
The uremic syndrome is attributed to the progressive retention of a large number of compounds which, under normal conditions, are excreted by healthy kidneys. The compounds are called uremic toxins when they interact negatively with biological functions.
Ziad A. Massy +2 more
doaj +1 more source
Newborn Urinary Metabolic Signatures of Prematurity and Other Disorders: A Case Control Study [PDF]
This work assesses the urinary metabolite signature of prematurity in newborns by nuclear magnetic resonance (NMR) spectroscopy, while establishing the role of possible confounders and signature specificity, through comparison to other disorders.
Sílvia O. Diaz +13 more
core +1 more source
Intestinal Microbiota, Probiotics and Mental Health: From Metchnikoff to Modern Advances: Part III – Convergence toward Clinical Trials [PDF]
Rapid scientific and technological advances have allowed for a more detailed understanding of the relevance of intestinal microbiota, and the entire body-wide microbiome, to human health and well-being.
Bested, Alison C +2 more
core +2 more sources
We present a comprehensive study of the interaction of human serum albumin (HSA) with poly(acrylic acid) (PAA; number average degree of polymerization: 25) in aqueous solution. The interaction of HSA with PAA is studied in dilute solution as the function
Ballauff, Matthias +7 more
core +1 more source
Biology of the microbiome 2: metabolic role [PDF]
The human microbiome is a new frontier in biology and one that is helping to define what it is to be human. Recently, we have begun to understand that the "communication" between the host and its microbiome is via a metabolic superhighway.
Li, Jia V. +2 more
core +2 more sources
Cardiorenal disease connection during post-menopause: The protective role of estrogen in uremic toxins induced microvascular dysfunction [PDF]
Female gender, post-menopause, chronic kidney disease (CKD) and (CKD linked) microvascular disease are important risk factors for developing heart failure with preserved ejection fraction (HFpEF).
Asselbergs, F.W. (Folkert) +7 more
core +5 more sources

