Results 91 to 100 of about 7,345 (172)

The Choice of Anti-Inflammatory Influences the Elimination of Protein-Bound Uremic Toxins

Toxins
Pain is a frequent and disturbing symptom among hemodialysis patients. Protein-bound uremic toxins (PBUTs) are related to cardiovascular and overall mortality, and they are difficult to remove with current hemodialysis treatments.
Víctor Joaquín Escudero-Saiz, Elena Cuadrado-Payán, María Rodriguez-Garcia, Gregori Casals, Lida María Rodas, Néstor Fontseré, María del Carmen Salgado, Carla Bastida, Nayra Rico, José Jesús Broseta, Francisco Maduell   +10 more
doaj   +1 more source

Indoxyl Sulfate Suppresses Hpdlc Osteogenesis Through Ferroptosis

International Dental Journal
Aim or purpose: Human periodontal ligament stem cells (hPDLCs) play pivotal roles in periodontal tissue repair and bone regeneration. This study investigated the inhibitory effects and underlying mechanisms of indoxyl sulfate (IS), a uremic toxin, on the
Huiwen Chen, Zhongchen Song
doaj   +1 more source

Switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, may substantially reduce serum urate levels, through URAT1 inhibition, potentially without adversely affecting ABCG2 function: findings from the SWITCH SURI study

Frontiers in Endocrinology
BackgroundDotinurad is a novel selective urate transporter 1 (URAT1) inhibitor recently introduced in Japan. This study aims to evaluate the efficacy and safety of dotinurad in hyperuricemic patients with type 2 diabetic kidney disease by comparing serum
Takeshi Osonoi, Shinichiro Shirabe, Miyoko Saito, Mitsuru Hosoya, Norie Watahiki, Satako Douguchi, Kensuke Ofuchi, Makoto Katoh, Makoto Katoh   +8 more
doaj   +1 more source

Trimethylamine N-oxide, S-equol, and indoxyl sulfate inflammatory microbiota players in ocular Behçet’s disease

Türk Biyokimya Dergisi
The aims of the study were to assess the levels of serum TMAO, S-equol, and indoxyl sulfate in subjects with ocular active Behçet’s disease (OABD) and ocular inactive Behçet’s disease (OIBD).
Arslan Sermal, Kaya Mehmet Kaan, Aydin Suna, Aydin Suleyman   +3 more
doaj   +1 more source

Uremic Toxicity of Indoxyl Sulfate

Uremic Toxicity of Indoxyl Sulfate
Indoxyl sulfate, a uremic toxin, is accumulated in the serum of chronic kidney disease (CKD) patients.A part of the dietary protein-derived tryptophan is metabolized into indole by tryptophanase in intestinal bacteria. Indole is absorbed into the blood from the intestine, and is metabolized to indoxyl sulfate in the liver.
openaire   +1 more source

Indoxyl Sulfate-Mediated Blood-Brain Barrier Damage in Chronic Kidney Disease. [PDF]

Toxins (Basel)
Hernandez L, Strizzi CT, Rosina M, Schwarz A, Kronqvist N, Arefin S, Stenvinkel P, Kublickiene K, MOMENTUM Consortium.   +8 more
europepmc   +1 more source

Indoxyl Sulfate, Cardiac Biomarkers, and Left Ventricular Wall Thickening in Cats with Chronic Kidney Disease. [PDF]

Vet Sci
Akbaba M, Bastan I, Bakar-Ates F, Terzi OS.   +3 more
europepmc   +1 more source

Indoxyl sulfate in the gut-kidney axis: from diet-microbiome interactions to renal injury and targeted therapies. [PDF]

Front Nutr
Huang X, Yang X, Huang J, Tao W, Yu Y, Yu R.   +5 more
europepmc   +1 more source

Effect of Dietary Aryl Hydrocarbon Receptor Ligands on Indoxyl Sulfate-Induced Endothelial Activation. [PDF]

Toxins (Basel)
Lefevre F, Chermiti R, Cebile J, McKay N, Bataille S, Burtey S, Dou L.   +6 more
europepmc   +1 more source

Indoxyl Sulfate Contributes to Progression of Renal Injury in the Postpartum Period Following Pregnancy-Related Acute Kidney Injury. [PDF]

Toxins (Basel)
Griffin A, Berry B, Melaku L, Johnson D, Guevarra P, Shack LA, Spencer SK, Nanduri B, Wallace K.   +8 more
europepmc   +1 more source