Results 61 to 70 of about 6,601,283 (299)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Critical Care, 2019 Background Sepsis is the leading cause of mortality for critically ill patients worldwide. Patients develop T lymphocyte dysfunctions leading to T-cell exhaustion associated with increased risk of death.
Julie Mouillaux +10 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Causes and research progress of earthquakes induced by industrial production
地球与行星物理论评In recent years, with continuous social and economic development, there has been an increase in the scale of reservoir impoundment and underground industrial development activities.
Zitao Wang, Zhongliang Wu, Huai Zhang
doaj +1 more source
Journal of Nonlinear Mathematical Physics, 2020 Induced dynamics is defined as dynamics of real zeros with respect to $x$ of equation $f(q_1-x,\ldots,q_N-x,p_1,\ldots,p_N)=0$, where $f$ is a function, and $q_i$ and $p_j$ are canonical variables obeying some (free) evolution. Identifying zero level lines with the world lines of particles, we show that the resulting dynamical system demonstrates ...
openaire +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
High-speed gas-solid two-phase flow erosion of 1Cr9Mo alloy
工程科学学报, 2016 A self-made gas-solid erosion testing apparatus driven by shock wave was used to investigate the wear properties of 1Cr9Mo steel commonly used as manufacturing materials in the coal chemical industry, and SiO2, Al2O3 and SiC particles were chosen as ...
OU Guo-fu +4 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Practical considerations for postarrest targeted temperature management
Turkish Journal of Emergency Medicine, 2020 Out-of-hospital cardiac arrest remains a major challenge worldwide, with survival to discharge rates of
Isabelle Mullen, Benjamin S Abella
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source