Results 211 to 220 of about 390,247 (379)

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

open access: yesAdvanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei   +11 more
wiley   +1 more source

Directed Differentiation of Human-Induced Pluripotent Stem Cells Generates Active Motor Neurons [PDF]

open access: bronze, 2009
Saravanan Karumbayaram   +12 more
openalex   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

Generation of Human-Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 [PDF]

open access: bronze, 2009
Wenlin Li   +9 more
openalex   +1 more source

Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke

open access: yesAdvanced Science, EarlyView.
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber   +6 more
wiley   +1 more source

Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells Survive and Integrate into 6-OHDA-Lesioned Rats [PDF]

open access: green, 2009
Jingli Cai   +5 more
openalex   +1 more source

Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix

open access: yesAdvanced Science, EarlyView.
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang   +16 more
wiley   +1 more source

Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells under Xeno-free Conditions [PDF]

open access: bronze, 2009
Ignasi Rodríguez-Pizà   +7 more
openalex   +1 more source

Home - About - Disclaimer - Privacy