Results 1 to 10 of about 288,397 (260)

Anti-Cancer Effects of Lactobacillus plantarum L-14 Cell-Free Extract on Human Malignant Melanoma A375 Cells

Molecules, 2020
Human malignant melanoma is the most aggressive type of skin cancer with high metastatic ability. Despite several traditional therapies, the mortality rate remains high. Lactobacillus plantarum (L.
Jaehyun Park, Mijin Kwon, Jaehoon Lee, Sangkyu Park, Jeongmin Seo, Sangho Roh   +5 more
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Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells

Scientific Reports, 2016
TINCR is a well-known lncRNA which acts as a master regulator in somatic differentiation development. However, it is still unclear whether TINCR is also involved in caner occurrence and progression.
Zhicong Chen, Yuchen Liu, Anbang He, Jianfa Li, Mingwei Chen, Yonghao Zhan, Junhao Lin, Chengle Zhuang, Li Liu, Guoping Zhao, Weiren Huang, Zhiming Cai   +11 more
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Myeloprotection by Cytidine Deaminase Gene Transfer in Antileukemic Therapy

Neoplasia: An International Journal for Oncology Research, 2013
Gene transfer of drug resistance (CTX-R) genes can be used to protect the hematopoietic system from the toxicity of anticancer chemotherapy and this concept recently has been proven by overexpression of a mutant O6-methylguaninemethyltransferase in the ...
Nico Lachmann, Sebastian Brennig, Ruhi Phaltane, Michael Flasshove, Dagmar Dilloo, Thomas Moritz   +5 more
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Cyclopamine, an Antagonist of Hedgehog (Hh) Signaling Pathway, Reduces the Hatching Rate of Parthenogenetic Murine Embryos

Journal of Animal Reproduction and Biotechnology, 2018
Hedgehog (Hh) pathway plays a key role in development from invertebrate to vertebrate. It is known to be involved in cell differentiation, polarity, proliferation, including the development of vertebrate limb and the establishment of flies’ body plan. To
Jaehyun Park, Jeonghyeon Moon, So Min, Stephan Chae, Sangho Roh   +4 more
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Lost in translation: pluripotent stem cell‐derived hematopoiesis

EMBO Molecular Medicine, 2015
Pluripotent stem cells (PSCs) such as embryonic stem cells or induced pluripotent stem cells represent a promising cell type to gain novel insights into human biology.
Mania Ackermann, Steffi Liebhaber, Jan‐Henning Klusmann, Nico Lachmann   +3 more
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Prognostic Values of Long Noncoding RNA GAS5 in Various Carcinomas: An Updated Systematic Review and Meta-Analysis

Frontiers in Physiology, 2017
The growth arrest-specific transcript 5 (GAS5) is a long noncoding RNA with low expression in multiple cancers. This meta-analysis aims to explore the association between GAS5 expression levels and cancer patients' prognosis.
Qunjun Gao, Qunjun Gao, Haibiao Xie, Haibiao Xie, Hengji Zhan, Hengji Zhan, Jianfa Li, Yuchen Liu, Weiren Huang   +8 more
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WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling

Nature Communications, 2019
WDFY2 is known as a tumour suppressor but its function is unclear. Here, the authors show that WDFY2 interacts with the v-SNARE VAMP3, leading to a suppression of the metalloprotease MT1-MMP secretion, suggesting that WDFY2 acts a tumour suppressor by ...
Marte Sneeggen, Nina Marie Pedersen, Coen Campsteijn, Ellen Margrethe Haugsten, Harald Stenmark, Kay Oliver Schink   +5 more
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Identifying drivers of breast cancer metastasis in progressively invasive subpopulations of zebrafish-xenografted MDA-MB-231

Molecular Biomedicine, 2022
Cancer metastasis is the primary cause of the high mortality rate among human cancers. Efforts to identify therapeutic agents targeting cancer metastasis frequently fail to demonstrate efficacy in clinical trials despite strong preclinical evidence ...
Jerry Xiao, Joseph R. McGill, Apsra Nasir, Alexander Lekan, Bailey Johnson, Devan J. Wilkins, Gray W. Pearson, Kandice Tanner, Hani Goodarzi, Eric Glasgow, Richard Schlegel, Seema Agarwal   +11 more
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Bioactive Lipid Signaling in Cardiovascular Disease, Development, and Regeneration

Cells, 2020
Cardiovascular disease (CVD) remains a leading cause of death globally. Understanding and characterizing the biochemical context of the cardiovascular system in health and disease is a necessary preliminary step for developing novel therapeutic ...
Aaron H. Wasserman, Manigandan Venkatesan, Aitor Aguirre   +2 more
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Corrigendum: Deepening the understanding of CNVs on chromosome 15q11–13 by using hiPSCs: An overview

Frontiers in Cell and Developmental Biology, 2023
Angela Maria Giada Giovenale, Angela Maria Giada Giovenale, Giorgia Ruotolo, Giorgia Ruotolo, Amata Amy Soriano, Elisa Maria Turco, Giovannina Rotundo, Alessia Casamassa, Angela D’Anzi, Angelo Luigi Vescovi, Angelo Luigi Vescovi, Jessica Rosati   +11 more
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