Results 21 to 30 of about 288,397 (260)
Past, Present, and Future of Direct Cell Reprogramming
, 2022 Budding off from the broader developmental biology and stem cell research fields, cellular reprogramming is now established as a prominent discipline in its own right.
Ahlenius, Henrik +2 more
core +1 more source
Gain-of-function oncogenic mutations in TP53 enhance defined factor-mediated cellular reprogramming [PDF]
, 2011 Cancer is a disorder with various genetic and epigenetic alterations. Genetic alterations such as mutations, i.e., substitutions, amplifications, and deletions of nucleotide sequences, are largely irreversible, whereas epigenetic alterations can be ...
Kazuyoshi Yamamoto +8 more
core +1 more source
Small Molecules Pushing Erythroid/Megakaryocyte Cell Specification Boundaries
, 2022 A combination of a MEK/ERK-signaling inhibitor and three chromatin-remodeling molecules enhances generation of platelet-producing megakaryocytes in vitro, possibly through direct ...
Flygare, Johan +2 more
core +2 more sources
Human Neural Stem Cells for Cell-Based Medicinal Products
Cells, 2021 Neural stem cells represent an attractive tool for the development of regenerative therapies and are being tested in clinical trials for several neurological disorders.
Beatriz Fernandez-Muñoz +3 more
doaj +1 more source
Multiplexed promoterless gene expression with CRISPReader
Genome Biology, 2019 Background Genes are comprised of DNA codes and contain promoters and other control elements for reading these codes. The rapid development of clustered regularly interspaced short palindromic repeats (CRISPR) technology has made possible the ...
Hengji Zhan +5 more
doaj +1 more source
A Dynamic Size Distributed Program Image Cache for Wireless Sensor Networks
, 2009 Reprogramming node software over-the-air is an essential requirement in many wireless sensor network applications due to the inaccessibility of the deployed sensor nodes.
De Roure, David +5 more
core +2 more sources
Epigenetic impairments in development of parthenogenetic preimplantation mouse embryos
The Journal of Reproduction and Development, 2018 Parthenogenesis is an activation process of oocytes that occur without the participation of sperm. Evidence suggests that normal development of embryos requires proper expression of several imprinted genes inherited from both the paternal and maternal ...
Ngan Thi Kim HO +3 more
doaj +1 more source
Stem Cell Research & Therapy, 2022 Background Bone has important functions in the body. Several researchers have reported that the polysaccharides and lipopolysaccharide derived from microbes can promote osteogenic differentiation of stem cells.
Hyewon Kim +6 more
doaj +1 more source
Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success [PDF]
, 2012 Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage.
Franchesca Dawn Houghton (171722) +44 more
core +2 more sources
Cells, 2023 Autophagy–the lysosomal degradation of cytoplasm–plays a central role in cellular homeostasis and protects cells from potentially harmful agents that may accumulate in the cytoplasm, including pathogens, protein aggregates, and dysfunctional organelles ...
Yan Zhen, Harald Stenmark
doaj +1 more source