Results 21 to 30 of about 205,281 (308)
Adversarial Reprogramming of Text Classification Neural Networks [PDF]
, 2019 Adversarial Reprogramming has demonstrated success in utilizing pre-trained neural network classifiers for alternative classification tasks without modification to the original network.
Dubnov, Shlomo +3 more
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The XEN of reprogramming [PDF]
Cell Research, 2016 Reprogramming to pluripotency has thus far required complex procedures involving nuclear transfer, cell fusion or genetic manipulation. Two recent papers from Hongkui Deng's group now show various cell types can be reprogrammed simply by chemicals through an extraembryonic endoderm-like phase instead of the primitive streak-like mesendoderm induced by ...
Ergin, Beyret +1 more
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Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis [PDF]
, 2019 © The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Xu, X., Li, G., Li, C., Zhang, J., Wang, Q., Simmons, D. K., Chen, X., Wijesena, N., Zhu, W., Wang, Z.,
Aluru, Neelakanteswar +20 more
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Cold Spring Harbor Perspectives in Biology, 2014 Nuclear reprogramming technology was first established more than 50 years ago. It can rejuvenate somatic cells by erasing the epigenetic memories and reconstructing a new pluripotent order. The recent discovery reviewed here that induced pluripotency can be achieved by a small set of transcription factors has opened up unprecedented opportunities in ...
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Age reprogramming: cell rejuvenation by partial reprogramming
Development, 2022 ABSTRACT ‘Age reprogramming’ refers to the process by which the molecular and cellular pathways of a cell that are subject to age-related decline are rejuvenated without passage through an embryonic stage. This process differs from the rejuvenation observed in differentiated derivatives of induced pluripotent stem cells, which involves ...
Prim B. Singh, Assem Zhakupova
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Human Neural Stem Cells for Cell-Based Medicinal Products
Cells, 2021 Neural stem cells represent an attractive tool for the development of regenerative therapies and are being tested in clinical trials for several neurological disorders.
Beatriz Fernandez-Muñoz +3 more
doaj +1 more source
Gain-of-function oncogenic mutations in TP53 enhance defined factor-mediated cellular reprogramming [PDF]
, 2011 Cancer is a disorder with various genetic and epigenetic alterations. Genetic alterations such as mutations, i.e., substitutions, amplifications, and deletions of nucleotide sequences, are largely irreversible, whereas epigenetic alterations can be ...
Dyah Laksmi Dewi +9 more
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Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine [PDF]
, 2011 Embryonic stem (ES) cells are of great interest as a model system for studying early developmental processes and because of their potential therapeutic applications in regenerative medicine.
Kim, Jonghwan, Orkin, Stuart
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Stem Cell Research & Therapy, 2022 Background Bone has important functions in the body. Several researchers have reported that the polysaccharides and lipopolysaccharide derived from microbes can promote osteogenic differentiation of stem cells.
Hyewon Kim +6 more
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Generation of a human iPS cell line from a patient with retinitis pigmentosa due to EYS mutation [PDF]
, 2018 Retinitis pigmentosa (RP) is an inherited retinal degenerative disease. Mutations in EYS have been associated with autosomal recessive RP. The human iPS cell line, CABi002-A, derived from peripheral blood mononuclear cells from a patient carrying a ...
Bhattacharya, Shomi S. +5 more
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