Scale up manufacturing approach for production of human induced pluripotent stem cell-derived islets using Vertical Wheel® bioreactors. [PDF]
Dadheech N+17 more
europepmc +1 more source
What's New? Adoptive cell therapy (ACT) with tumor antigen‐specific CD8+ T cells has shown success in clinical trials treating patients with advanced or metastatic melanoma. Here, the authors established protocols for generating CD8+ T cells from human induced pluripotent stem cells (hiPSCs) expressing a melanoma‐specific T cell receptor (TCR) or ...
Juliane Poelchen+13 more
wiley +1 more source
From induced pluripotent stem cell (iPSC) to universal immune cells: literature review of advances in a new generation of tumor therapies. [PDF]
Zhang J+9 more
europepmc +1 more source
Organoid‐tissue extracellular vesicles
Abstract Extracellular vesicles (EVs) are lipid bilayer structures secreted by cells that act as intercellular messengers. Tissue‐derived EVs (TEVs), harvested from the tissue interstitium, directly reflect the actual physiological or pathological state of the tissue microenvironment.
Han Liu+6 more
wiley +1 more source
A human induced pluripotent stem cell toolbox for studying sex chromosome effects
Meleckyte R+9 more
europepmc +1 more source
Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury. [PDF]
Vidman S+3 more
europepmc +1 more source
Developmental Imaging of Radish Sprouts Using Dynamic Optical Coherence Tomography
We non‐invasively investigated the germination process of radish sprouts for up to 12 days using volumetric dynamic optical coherence tomography (OCT). This technique analyzes temporal fluctuation in the OCT signal. The dynamic OCT signals in the vessels and growing roots were initially high and decreased with tissue maturation.
Yiheng Lim+5 more
wiley +1 more source
Establishing a context of use for three-dimensional cardiac tissue derived from human-induced pluripotent stem cell-derived cardiomyocytes using inotropes. [PDF]
Okai Y+10 more
europepmc +1 more source
Fluorescence Lifetime Imaging Techniques—A Review on Principles, Applications and Clinical Relevance
This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities and typical applications in biology and clinical studies. ABSTRACT This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities, and typical applications ...
V. I. Shcheslavskiy+5 more
wiley +1 more source