Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Prelle, Katja+4 more
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Variability of human pluripotent stem cell lines. [PDF]
Human pluripotent stem cells derived from embryos (human Embryonic Stem Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining ...
Ortmann, Daniel, Vallier, Ludovic
core +1 more source
Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. [PDF]
Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal ...
Awe, Jason P+9 more
core +3 more sources
Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark+2 more
core
Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits. [PDF]
The cardiac transcription factor (TF) gene NKX2-5 has been associated with electrocardiographic (EKG) traits through genome-wide association studies (GWASs), but the extent to which differential binding of NKX2-5 at common regulatory variants contributes
Benaglio, Paola+17 more
core
A comprehensive analysis of induced pluripotent stem cell (iPSC) production and applications. [PDF]
Matiukhova M+7 more
europepmc +1 more source
Human induced pluripotent stem cell models for Alzheimer's disease research: a bibliometric analysis. [PDF]
Sun Y+7 more
europepmc +1 more source
Maturation of human induced pluripotent stem cell-derived cardiomyocytes promoted by Brachyury priming. [PDF]
Kargaran PK+8 more
europepmc +1 more source
Differentiation, Maintenance, and Contraction Profiling of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. [PDF]
Snelders M, van der Pluijm I, Essers J.
europepmc +1 more source
Topological data analysis of pattern formation of human induced pluripotent stem cell colonies. [PDF]
Hartsock I+6 more
europepmc +1 more source